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Biology B (21st Century) · OCR J257 · Breadth in Biology · Higher · June 2024

OCR GCSE Biology B (21st Century) Breadth in Biology Higher June 2024 question paper J257/03

1h 45m 90 marks

OCR J257 · Paper 3

11 questions
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Question 1

A student is investigating how light intensity affects the rate of photosynthesis.

(a)
(a)(i)
Figure for question 1

[3]

Answer
Mark scheme for question 1(a)(i)
(a)(ii)

Fig. 1.2 shows a different set of equipment that can be used.

Figure for question 1

A second student suggests that the equipment shown in Fig. 1.2 will improve the investigation.

Explain why.

[2]

Answer
Mark scheme for question 1(a)(ii)
(b)

Fig. 1.3 shows the effect of changing the light intensity on the rate of photosynthesis.

Figure for question 1

Which section or sections of the graph in Fig. 1.3 show the relationship y = mx + c ?

Tick (✓) one box.

Question 1, shown as an image

[1]

Answer
Mark scheme for question 1(b)

Question 2

The diagram shows the feeding relationships of some of the organisms that live in an Arctic ecosystem.

Figure for question 2
Question 2, shown as an image
Figure for question 2
(a)

What does each picture in the food web represent?

Tick (✓) one box.

Question 2, shown as an image

[1]

Answer
Mark scheme for question 2(a)
(b)

Complete each sentence by writing in the correct number.

There are........ producers in the food web.

There are........ herbivores in the food web.

The arctic fox is in trophic level........

[3]

Answer
Mark scheme for question 2(b)
(c)

A lemming has a mass of 82 g. An arctic fox eats the lemming, but only consumes 75 g of the lemming.

Calculate the percentage mass the arctic fox has consumed.

Give your answer to 3 significant figures.

[3]

Answer
Mark scheme for question 2(c)
(d)

When lemmings are in short supply, the arctic fox will eat eggs.

(d)(i)

Eggs contain protein.

Which reagent is used to test for protein?

[1]

Answer
Mark scheme for question 2(d)(i)
(d)(ii)
Figure for question 2

[2]

Answer
Mark scheme for question 2(d)(ii)
(d)(iii)

A student calculates the surface area and volume of an egg.

Surface area of the egg = 67.5 cm2

Volume of the egg = 50 cm3

Show that the surface area to volume ratio of the egg is 1.35: 1.

[2]

Answer
Mark scheme for question 2(d)(iii)

Question 3

(a)

Sam is visiting Norway where the average temperature in the winter is –6.8 °C.

Sam steps outside the hotel wearing only a jumper.

Complete the sentences to describe the processes that the body will use to regulate Sam’s body temperature.

Use words from the list.

glands hypothalamus muscles pituitary

receptors shivering skin cells sweating

The external temperature is detected by........ in the skin.

An electrical impulse is sent to the........ which coordinates a response.

An electrical impulse is sent from the coordinator to the........

The body will respond by........

[4]

Answer
Mark scheme for question 3(a)
(b)

Which method of cooling the human body would be the least effective in a hot humid environment ? Explain your answer.

Method........

Explanation........

[3]

Answer
Mark scheme for question 3(b)
(c)

Explain the importance of maintaining a constant internal temperature.

[2]

Answer
Mark scheme for question 3(c)

Question 4

A student is investigating the distribution of stomata on leaf surfaces.

The student removes 4 leaves from the same plant.

Leaf 1 – they cover the lower surface of the leaf in waterproof grease. Leaf 2 – they cover the upper surface of the leaf in waterproof grease. Leaf 3 – they cover both surfaces of the leaf in waterproof grease. Leaf 4 – neither surface of the leaf is covered in waterproof grease.

The results of the experiment are shown in the diagram

Figure for question 4
(a)

Explain why applying waterproof grease to both sides of the leaf prevented wilting.

[2]

Answer
Mark scheme for question 4(a)
(b)

The student looks at the results and writes this conclusion:

Figure for question 4

Explain how the results of the investigation support the student’s conclusion.

[2]

Answer
Mark scheme for question 4(b)
(c)

Which structure brings water to the leaf from the roots?

[1]

Answer
Mark scheme for question 4(c)

Question 5

Rats are considered a pest to many farmers as they eat their crops.

A chemical called warfarin can be used to kill rats.

Some rats developed a natural resistance to warfarin.

(a)

What is the most likely cause of this resistance?

[1]

Answer
Mark scheme for question 5(a)
(b)

Complete the sentences to explain how more rats developed resistance to warfarin.

Use words from the list.

allele die genome reproduce

respire ribosome survive

Rats that were resistant to the warfarin were more likely to........ and

........ and therefore pass on the........ for resistance to their offspring.

[3]

Answer
Mark scheme for question 5(b)
(c)

State the names of the two scientists who developed the theory of evolution by natural selection.

[1]

Answer
Mark scheme for question 5(c)
(d)

Explain why some people do not accept this modern theory of evolution.

[1]

Answer
Mark scheme for question 5(d)

Question 6

(a)

The human body has two communication systems:

• the hormonal system

• the nervous system.

State two ways that the response generated by the hormonal system is different to the response generated by the nervous system.

[2]

Answer
Mark scheme for question 6(a)
(b)

ADH is a hormone that controls the water balance in the body.

Draw lines to connect each question with the correct answer.

Figure for question 6

[2]

Answer
Mark scheme for question 6(b)
(c)

What effect will body fluids that contain too much water have on cells?

[3]

Answer
Mark scheme for question 6(c)

Question 7

Some babies are born with cataracts.

(a)

Cataracts affect the lens.

What role does the lens have in the functioning of the eye?

[1]

Answer
Mark scheme for question 7(a)
(b)

Surgical removal of cataracts in babies can be done, but there may be problems after surgery.

In a trial, scientists removed the lens from 12 babies with cataracts but left behind the stem cells.

All the babies grew a new lens within 3 months.

(b)(i)

Explain how the new lens grew from the stem cells.

[2]

Answer
Mark scheme for question 7(b)(i)
(b)(ii)

Suggest why some parents may be concerned about this trial procedure being used on their babies.

[1]

Answer
Mark scheme for question 7(b)(ii)

Question 8

Salmonella is a communicable disease caused by bacteria.

Salmonella bacteria can enter the body in contaminated food.

A doctor sees a patient with symptoms that suggest they have food poisoning caused by Salmonella bacteria.

The doctor decides to take a sample from the patient to send to a laboratory for further testing.

(a)

Suggest a suitable sample that could be taken from the patient that can be tested for Salmonella bacteria.

[1]

Answer
Mark scheme for question 8(a)
(b)

When the sample arrives at the laboratory the scientists first make a culture of the bacteria.

Explain why the scientists make a culture.

[2]

Answer
Mark scheme for question 8(b)
(c)

The scientists take a sample from the culture.

They prepare a slide so they can view the bacteria.

They use a stain that turns Salmonella bacteria pink.

Describe how the scientist can use a light microscope to determine if the patient’s symptoms are caused by Salmonella.

[3]

Answer
Mark scheme for question 8(c)
(d)

Explain why it is important that aseptic techniques are used at all stages of the procedure.

[1]

Answer
Mark scheme for question 8(d)
(e)

Bacteria reproduce asexually.

(e)(i)

State one advantage of asexual reproduction.

[1]

Answer
Mark scheme for question 8(e)(i)
(e)(ii)

State one disadvantage of asexual reproduction.

[1]

Answer
Mark scheme for question 8(e)(ii)

Question 9

(a)

Monoclonal antibodies can be produced in the laboratory and used to treat disease.

Put statements A to E in the correct order to describe how monoclonal antibodies are made.

A Antibody producing cells are removed from the animal.

B Antigens are injected into an animal.

C Cells are cultured to produce clones.

D Cells producing the correct antibody are selected.

E White blood cells which produce the antibodies are made by the animal.

Write one letter in each box.

One has been done for you.

Figure for question 9

[3]

Answer
Mark scheme for question 9(a)
(b)

Draw a line to connect each disease to the type of pathogen that causes the disease.

Figure for question 9

[3]

Answer
Mark scheme for question 9(b)
(c)

The United Nations collects data on global diseases.

The table shows regional data about the number of new HIV infections in 2022.

RegionEstimated number of new HIV infections
Asia and the Pacific3.0 × 105
Caribbean1.6 × 104
Eastern and Southern Africa5.0 × 105
Eastern Europe and central Asia1.6 × 105
Latin America1.1 × 105
Middle East and North Africa1.7 × 104
Western and central Africa1.6 × 105
Western and central Europe and North America5.8 × 104
(c)(i)

Which region had the highest estimated number of new HIV infections in 2022?

[1]

Answer
Mark scheme for question 9(c)(i)
(c)(ii)

Suggest two reasons why the number of HIV infections was greater in this region than in other regions.

[2]

Answer
Mark scheme for question 9(c)(ii)
(c)(iii)

The data provided by the United Nations is an estimation and is not the actual number of new HIV infections.

Explain why the data is only an estimation.

[2]

Answer
Mark scheme for question 9(c)(iii)
(c)(iv)

HIV destroys an important type of white blood cell called CD4. The ‘normal’ range for CD4 white blood cells is 800–1200 cells per mm3 of blood.

One particular person living with HIV has <200 CD4 cells per mm3.

Describe the likely impact of this on the person’s health.

[1]

Answer
Mark scheme for question 9(c)(iv)

Question 10

Figure for question 10
(a)

State two differences between the projections made in 1975 and those made in 2020.

[2]

Answer
Mark scheme for question 10(a)
(b)

Suggest why the United Nations revises their projections regularly.

[1]

Answer
Mark scheme for question 10(b)
(c)

Scientists are concerned about food security for future generations.

Describe two biological factors that affect food security.

[2]

Answer
Mark scheme for question 10(c)
(d)

Scientists think genetic engineering may be one solution for the food security problem.

Scientists have genetically engineered rice to contain beta carotene, which the body can use to make vitamin A.

The diagram shows stages involved in this process.

Gene for beta carotene is

Figure for question 10

The bacteria are added to a petri dish containing rice embryos. They ‘infect’ the embryos and transfer the

Figure for question 10

Genetically engineered rice plants are crossed with strains of rice that grow locally.

(d)(i)

Explain why it is important that only the gene that is required from the daffodil is removed from the daffodil DNA.

[2]

Answer
Mark scheme for question 10(d)(i)
(d)(ii)

Explain why the scientists replicate the genes that have been isolated before inserting them into the plasmids.

[1]

Answer
Mark scheme for question 10(d)(ii)
(d)(iii)

What vector is used to genetically engineer rice?

[1]

Answer
Mark scheme for question 10(d)(iii)
(d)(iv)

Suggest why the genetically engineered rice plants are crossed with strains of rice that already grow locally.

[1]

Answer
Mark scheme for question 10(d)(iv)

Question 11

PKD (Polycystic Kidney Disease) is a genetic condition found in cats. It is caused by a dominant allele of a single gene.

(a)

Explain why cat breeders will be more concerned about a genetic condition that is caused by a dominant allele than a recessive allele.

[2]

Answer
Mark scheme for question 11(a)
(b)

A male cat which is homozygous recessive mates with a female cat that is heterozygous for PKD.

(b)(i)

Show how these cats could produce kittens that have PKD.

Use a Punnett square.

Use D to represent the dominant allele and d to represent the recessive allele.

[4]

Answer
Mark scheme for question 11(b)(i)
(b)(ii)

When the male homozygous recessive cat mates with the female heterozygous cat, they have 2 kittens.

Calculate the probability that both kittens have PKD.

[2]

Answer
Mark scheme for question 11(b)(ii)
(c)

The cat breeder could use genome sequencing to determine which of the kittens has PKD. Genome sequencing costs a lot of money.

Suggest why the cat breeder decides to spend this money.

[1]

Answer
Mark scheme for question 11(c)
(d)

Cats have 38 chromosomes in a body cell.

How many chromosomes will a cat have in a sperm cell?

Tick (✓) one box

Question 11, shown as an image

[1]

Answer
Mark scheme for question 11(d)

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