BREAKING
Local teen gets 6-7 in science, entire class screams★Student has two science teachers, asks the wrong one again★Required practical fails, teacher calls it ‘valid data’★
  1. Home
  2. GCSE
  3. Combined Science: Synergy - AQA
  4. Cell structure

AQA GCSE Combined Science: Synergy

Topic questions Cell biology Cell structure

Cell structure

12 questions · 159 marks · about 3 hours

Cell structure questions

AQA 8465 Cell structure 12 questions

Paper 2: Life and environmental sciences June 2025 Foundation tier, Question 9 18 marks

Figure 9 shows a human egg cell viewed using a light microscope.

Figure for question 9
9.1

In Figure 9, the diameter of the image of the egg is 38 mm.

The magnification of Figure 9 is × 400

Calculate the real diameter of the egg cell in micrometres.

Use the equation:

Question 9, shown as an image

1 millimetre = 1000 micrometres

Real diameter of egg cell = _____________________ micrometres

[4]
Reveal mark scheme Mark scheme for question 9.1
9.2

Draw a simple diagram of the egg cell shown in Figure 9.

On your drawing:

maths symbol $l~bel two parts of the egg cell that are visible in Figure 9

maths symbol $do not include other cells.

[2]
Reveal mark scheme Mark scheme for question 9.2
9.3

Some parts of a human egg cell are not visible in Figure 9.

Name one part of a human egg cell that is only visible using an electron microscope.

[1]
Reveal mark scheme Mark scheme for question 9.3
9.4

Name the process of cell division that produces egg cells.

[1]
Reveal mark scheme Mark scheme for question 9.4
9.5

How many chromosomes are in a human egg cell?

[1]
Reveal mark scheme Mark scheme for question 9.5
9.6

Describe how a chromosome in a sperm cell determines whether the offspring that forms is male or female.

[2]
Reveal mark scheme Mark scheme for question 9.6
9.7

maths symbol

Which hormone stimulates the release of an egg?

Tick (maths symbol) one box.

FSH

LH

Oestrogen

[1]
Reveal mark scheme Mark scheme for question 9.7
9.8

Oral contraceptive pills contain hormones that prevent the release of an egg.

Scientists studied the effectiveness of different types of contraception with perfect use and with use in real life.

maths symbol ‘Perfect use’ means following all the instructions.

maths symbol ‘Use in real life’ is what actually happens in the population. The instructions may not always be followed in real life.

Figure 10 shows the results.

Figure for question 9

Evaluate the effectiveness of the three types of contraception shown in Figure 10.

Use data from Figure 10.

[6]
Reveal mark scheme Mark scheme for question 9.8

Paper 2: Life and environmental sciences June 2025 Higher tier, Question 1 18 marks

Figure 1 shows a human egg cell viewed using a light microscope.

Figure for question 1
1.1

In Figure 1, the diameter of the image of the egg is 38 mm.

The magnification of Figure 1 is × 400

Calculate the real diameter of the egg cell in micrometres.

Use the equation:

Question 1, shown as an image

1 millimetre = 1000 micrometres

Real diameter of egg cell = _____________________ micrometres

[4]
Reveal mark scheme Mark scheme for question 1.1
1.2

Draw a simple diagram of the egg cell shown in Figure 1.

On your drawing:

maths symbol $l~bel two parts of the egg cell that are visible in Figure 1

maths symbol $do not include other cells.

[2]
Reveal mark scheme Mark scheme for question 1.2
1.3

Some parts of a human egg cell are not visible in Figure 1.

Name one part of a human egg cell that is only visible using an electron microscope.

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

Name the process of cell division that produces egg cells.

[1]
Reveal mark scheme Mark scheme for question 1.4
1.5

How many chromosomes are in a human egg cell?

[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

Describe how a chromosome in a sperm cell determines whether the offspring that forms is male or female.

[2]
Reveal mark scheme Mark scheme for question 1.6
1.7

maths symbol

Which hormone stimulates the release of an egg?

Tick (maths symbol) one box.

FSH

LH

Oestrogen

[1]
Reveal mark scheme Mark scheme for question 1.7
1.8

Oral contraceptive pills contain hormones that prevent the release of an egg.

Scientists studied the effectiveness of different types of contraception with perfect use and with use in real life.

maths symbol ‘Perfect use’ means following all the instructions.

maths symbol ‘Use in real life’ is what actually happens in the population. The instructions may not always be followed in real life.

Figure 2 shows the results.

Figure for question 1

Evaluate the effectiveness of the three types of contraception shown in Figure 2.

Use data from Figure 2.

[6]
Reveal mark scheme Mark scheme for question 1.8

Paper 1: Life and environmental sciences June 2024 Foundation tier, Question 8 11 marks

Bacteria can cause disease.

Bacterial cells do not have a nucleus.

8.1

Which term describes bacterial cells?

Tick (✓) one box.

Eukaryotic

Fungal

Prokaryotic

[1]
Reveal mark scheme Mark scheme for question 8.1
8.2

Bacterial cells have no nucleus and are smaller than animal cells.

Give one other difference between bacterial cells and animal cells.

[1]
Reveal mark scheme Mark scheme for question 8.2
8.3

Escherichia coli (E. coli) is a type of bacterium.

E. coli causes symptoms of food poisoning.

Water companies sterilise rain water to produce drinking water.

The drinking water is then transported to homes in underground pipes.

Flooding can cause contamination of the drinking water by E. coli.

Suggest how people should treat drinking water at home if there is a risk of E. coli contamination.

[1]
Reveal mark scheme Mark scheme for question 8.3
8.4

Figure 11 shows two graphs:

maths symbol The rainfall in one town in one month.

maths symbol The number of cases of E. coli in the town in the same month.

Figure for question 8

The rainfall on day 12 was greater than on day 10.

Calculate how many times greater.

[3]
Reveal mark scheme Mark scheme for question 8.4
8.5

Symptoms of E. coli infection usually occur 5 days after infection.

A scientist stated:

‘Increased rainfall causes an increase in the number of cases of E. coli.’

Describe one piece of evidence from Figure 11 that supports the scientist’s statement.

[1]
Reveal mark scheme Mark scheme for question 8.5
8.6

Why might the number of cases of E. coli infection increase in the future?

Tick (✓) one box.

Climate change is causing loss of habitats for wildlife.

Climate change is causing more extreme rainfall.

Climate change is causing sea-levels to be lower.

[1]
Reveal mark scheme Mark scheme for question 8.6
8.7

Climate change is caused by an increase in the concentration of greenhouse gases in the atmosphere.

Carbon dioxide is a greenhouse gas.

Name two other greenhouse gases.

Do not refer to carbon dioxide in your answer.

[2]
Reveal mark scheme Mark scheme for question 8.7
8.8

Describe one way the rate of increase in carbon dioxide concentration in the atmosphere could be reduced.

[1]
Reveal mark scheme Mark scheme for question 8.8

Paper 1: Life and environmental sciences June 2024 Higher tier, Question 1 11 marks

Bacteria can cause disease.

Bacterial cells do not have a nucleus.

1.1

Which term describes bacterial cells?

Tick (✓) one box.

Eukaryotic

Fungal

Prokaryotic

[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

Bacterial cells have no nucleus and are smaller than animal cells.

Give one other difference between bacterial cells and animal cells.

[1]
Reveal mark scheme Mark scheme for question 1.2
1.3

Escherichia coli (E. coli) is a type of bacterium.

E. coli causes symptoms of food poisoning.

Water companies sterilise rain water to produce drinking water.

The drinking water is then transported to homes in underground pipes.

Flooding can cause contamination of the drinking water by E. coli.

Suggest how people should treat drinking water at home if there is a risk of E. coli contamination.

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

Figure 1 shows two graphs:

maths symbol The rainfall in one town in one month.

maths symbol The number of cases of E. coli in the town in the same month.

Figure for question 1

The rainfall on day 12 was greater than on day 10.

Calculate how many times greater.

[3]
Reveal mark scheme Mark scheme for question 1.4
1.5

Symptoms of E. coli infection usually occur 5 days after infection.

A scientist stated:

‘Increased rainfall causes an increase in the number of cases of E. coli.’

Describe one piece of evidence from Figure 1 that supports the scientist’s statement.

[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

Why might the number of cases of E. coli infection increase in the future?

Tick (✓) one box.

Climate change is causing loss of habitats for wildlife.

Climate change is causing more extreme rainfall.

Climate change is causing sea-levels to be lower.

[1]
Reveal mark scheme Mark scheme for question 1.6
1.7

Climate change is caused by an increase in the concentration of greenhouse gases in the atmosphere.

Carbon dioxide is a greenhouse gas.

Name two other greenhouse gases.

Do not refer to carbon dioxide in your answer.

[2]
Reveal mark scheme Mark scheme for question 1.7
1.8

Describe one way the rate of increase in carbon dioxide concentration in the atmosphere could be reduced.

[1]
Reveal mark scheme Mark scheme for question 1.8

Paper 2: Life and environmental sciences June 2024 Foundation tier, Question 4 15 marks

Figure 5 shows a green pepper growing on a pepper plant.

Figure for question 4
4.1
Figure for question 4
[2]
Reveal mark scheme Mark scheme for question 4.1
4.2

Figure 6 shows a drawing of a cell from a pepper.

Figure for question 4

Cell part A contains a green pigment.

Label parts A, B and C on Figure 6.

Choose answers from the box.

Figure for question 4
[3]
Reveal mark scheme Mark scheme for question 4.2
4.3
Figure for question 4 Figure for question 4
[2]
Reveal mark scheme Mark scheme for question 4.3
4.4

Water can move into cells and out of cells.

A student investigated how different concentrations of sugar solution affect the mass of pepper tissue.

This is the method used.

1. Cut three pieces of pepper 1 cm wide and 1 cm long.

2. Dry each piece.

3. Record the mass of each piece.

4. Leave each piece in sugar solution for 1 hour.

5. Remove the pieces from the sugar solution and dry each piece.

6. Record the mass of each piece.

7. Repeat steps 1 to 6 using different concentrations of sugar solution.

Before the investigation, the pepper was wrapped in plastic and kept at 5 °C.

Which are two reasons for keeping the pepper wrapped in plastic at 5 °C?

Tick (✓) two boxes.

To change the colour of the pepper

To decrease the size of the pepper

To increase growth of the pepper

To reduce water loss from the pepper

To slow down decay of the pepper

[2]
Reveal mark scheme Mark scheme for question 4.4
4.5

The student calculated the mean percentage change in mass at each concentration of sugar solution.

Figure 7 shows the results.

Figure 7

Question 4, shown as an image

Concentration

Question 4, shown as an image

–10

–20

In some concentrations of sugar solution, the mass of the pieces of pepper increased.

The mass increased because water moved into the cells.

What process moved water into the cells?

[1]
Reveal mark scheme Mark scheme for question 4.5
4.6

What concentration of sugar solution would cause a mean percentage change in mass of 0%?

Use Figure 7.

Concentration of sugar solution = __________________ arbitrary units

[1]
Reveal mark scheme Mark scheme for question 4.6
4.7

The cells of the pepper have wrinkled cell walls.

What is the advantage of wrinkled cell walls to the pepper plant?

Tick (✓) one box.

The cells can expand

The cells contain less cellulose

The surface area is smaller

[1]
Reveal mark scheme Mark scheme for question 4.7
4.8

Tobacco mosaic virus (TMV) can infect pepper plants.

Infected plants have yellow patches on the leaves.

Explain why plants with TMV grow slower than plants that do not have TMV.

[3]
Reveal mark scheme Mark scheme for question 4.8

Paper 2: Life and environmental sciences June 2023 Foundation tier, Question 7 17 marks

All living organisms are made of cells.

Figure 15 shows two types of cell.

Figure for question 7
7.1

Calculate how many times longer the liver cell is than the bacterial cell.

[2]
Reveal mark scheme Mark scheme for question 7.1
7.2

Compare the structure of cell A with the structure of cell B.

You should include similarities and differences in your answer.

Do not refer to cell size.

[4]
Reveal mark scheme Mark scheme for question 7.2
7.3

In multicellular organisms, cells are organised into tissues.

What is meant by a ‘tissue’?

[1]
Reveal mark scheme Mark scheme for question 7.3
7.4

A scientist investigated the effect of different concentrations of sugar solution on red blood cells.

Figure 16 shows the effect of placing a red blood cell into a sugar solution.

Figure for question 7

What conclusion can be made from the result in Figure 16 ?

Tick (✓) one box.

The sugar solution was less concentrated than inside the cell.

The sugar solution was the same concentration as inside the cell.

The sugar solution was more concentrated than inside the cell.

[1]
Reveal mark scheme Mark scheme for question 7.4
7.5

A student investigated the effect of different concentrations of sugar solution on the change in mass of plant tissue.

The student used pieces of potato.

Describe a method the student could use to produce valid results.

[6]
Reveal mark scheme Mark scheme for question 7.5
7.6

The student used a valid method.

The student calculated the percentage change in mass of the pieces of potato.

Table 5 shows the results.

Figure for question 7

Complete Figure 17.

You should:

maths symbol plot the data from Table 5

maths symbol draw a line of best fit.

Some of the results have been plotted for you.

Figure for question 7
[2]
Reveal mark scheme Mark scheme for question 7.6
7.7

Determine the concentration of sugar solution that would cause no change in the mass of a piece of the potato.

Use Figure 17.

Concentration of sugar solution = _________________________ mol/dm3

[1]
Reveal mark scheme Mark scheme for question 7.7

Paper 2: Life and environmental sciences June 2023 Higher tier, Question 1 17 marks

All living organisms are made of cells.

Figure 1 shows two types of cell.

Figure for question 1
1.1

Calculate how many times longer the liver cell is than the bacterial cell.

[2]
Reveal mark scheme Mark scheme for question 1.1
1.2

Compare the structure of cell A with the structure of cell B.

You should include similarities and differences in your answer.

Do not refer to cell size.

[4]
Reveal mark scheme Mark scheme for question 1.2
1.3

In multicellular organisms, cells are organised into tissues.

What is meant by a ‘tissue’?

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

A scientist investigated the effect of different concentrations of sugar solution on red blood cells.

Figure 2 shows the effect of placing a red blood cell into a sugar solution.

Figure for question 1

What conclusion can be made from the result in Figure 2 ?

Tick (✓) one box.

The sugar solution was less concentrated than inside the cell.

The sugar solution was the same concentration as inside the cell.

The sugar solution was more concentrated than inside the cell.

[1]
Reveal mark scheme Mark scheme for question 1.4
1.5

A student investigated the effect of different concentrations of sugar solution on the change in mass of plant tissue.

The student used pieces of potato.

Describe a method the student could use to produce valid results.

[6]
Reveal mark scheme Mark scheme for question 1.5
1.6

The student used a valid method.

The student calculated the percentage change in mass of the pieces of potato.

Table 1 shows the results.

Figure for question 1

Complete Figure 3.

You should:

maths symbol plot the data from Table 1

maths symbol draw a line of best fit.

Some of the results have been plotted for you.

Figure for question 1
[2]
Reveal mark scheme Mark scheme for question 1.6
1.7

Determine the concentration of sugar solution that would cause no change in the mass of a piece of the potato.

Use Figure 3.

Concentration of sugar solution = _________________________ mol/dm3

[1]
Reveal mark scheme Mark scheme for question 1.7

Paper 2: Life and environmental sciences November 2021 Higher tier, Question 4 15 marks

Heart tissue is made of cardiac muscle cells.

Figure 2 shows a cardiac muscle cell.

Figure for question 4
4.1

Cardiac muscle needs to contract and relax continuously.

Cardiac muscle cells contain a large number of the structures labelled A.

Name structure A.

[1]
Reveal mark scheme Mark scheme for question 4.1
4.2

Oxygen moves from the cytoplasm into structure A by the process of diffusion.

Why does the oxygen move by diffusion?

[1]
Reveal mark scheme Mark scheme for question 4.2
4.3

Which change would cause the rate of diffusion of oxygen across an exchange surface to decrease?

Tick (✓) one box.

An increase in the surface area of the exchange surface

An increase in the temperature of the cell

An increase in the thickness of the exchange surface

[1]
Reveal mark scheme Mark scheme for question 4.3
4.4

The cardiac muscle cells in humans can respire aerobically and anaerobically. maths symbol Aerobic respiration uses oxygen. maths symbol Anaerobic respiration does not use oxygen.

Compare the processes of aerobic respiration and anaerobic respiration.

Do not refer to oxygen in your answer.

[4]
Reveal mark scheme Mark scheme for question 4.4
4.5

Figure 3 shows a diagram of a human heart.

Figure for question 4

What is the name of blood vessel X ?

Tick (✓) one box.

Aorta

Pulmonary artery

Pulmonary vein

Vena cava

[1]
Reveal mark scheme Mark scheme for question 4.5
4.6

Give one difference in the composition of the blood in the right ventricle compared with the blood in the left ventricle.

[1]
Reveal mark scheme Mark scheme for question 4.6
4.7

When the walls of the atria and ventricles contract, the pressure increases.

Table 4 shows information about the pressure during one contraction of the heart.

Figure for question 4

The left ventricle has the highest pressure.

Why does the left ventricle need to have the highest pressure?

[1]
Reveal mark scheme Mark scheme for question 4.7
4.8

What is the most likely maximum pressure in the right atrium?

Use Table 4.

Tick (✓) one box.

< 25 = 25 > 25

[1]
Reveal mark scheme Mark scheme for question 4.8
4.9

Some people have a medical condition called a ‘hole in the heart’.

A ‘hole in the heart’ is a small hole between the right ventricle and the left ventricle.

Some blood flows from the right ventricle to the left ventricle.

Explain why a ‘hole in the heart’ causes a person to feel tired.

[4]
Reveal mark scheme Mark scheme for question 4.9

Paper 1: Life and environmental sciences November 2020 Foundation tier, Question 2 9 marks

Figure 3 shows a human bone cell.

Figure for question 2
2.1

Label the cell structures A, B and C on Figure 3.

[3]
Reveal mark scheme Mark scheme for question 2.1
2.2

Which structure in the cell contains DNA?

Tick (✓) one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.2
2.3

A student used a microscope to view a cell.

The length of the image of the cell was 40 mm

The real length of the cell was 0.25 mm

Calculate the magnification of the image.

Use the equation:

Question 2, shown as an image

Magnification = ×

[2]
Reveal mark scheme Mark scheme for question 2.3
2.4

Root hair cells are found on the roots of plants.

Root hair cells do not photosynthesise.

Give one structure found in a leaf cell, but not in a root hair cell.

[1]
Reveal mark scheme Mark scheme for question 2.4
2.5

Which two structures are found in plant cells but not in animal cells?

Tick (✓) two boxes.

Figure for question 2
[2]
Reveal mark scheme Mark scheme for question 2.5

Paper 1: Life and environmental sciences November 2020 Foundation tier, Question 7 8 marks

Escherichia coli (E. coli) is a species of bacteria that can cause food poisoning.

7.1

Which term describes E. coli cells?

Tick (✓) one box.

Figure for question 7
[1]
Reveal mark scheme Mark scheme for question 7.1
7.2
Figure for question 7 Figure for question 7 Figure for question 7
[2]
Reveal mark scheme Mark scheme for question 7.2
7.3

Antibiotics are used to treat many different bacterial infections.

The government wants scientists to research and develop a new ‘antibiotic test’ that:

• takes less than 30 minutes

• shows doctors if an antibiotic is needed for an infection

• shows doctors which antibiotic to use.

Suggest two reasons why research into antibiotics is needed.

[2]
Reveal mark scheme Mark scheme for question 7.3
7.4

The new test should mean that fewer people take antibiotics.

What are two effects of fewer people taking antibiotics?

Tick (✓) two boxes.

Figure for question 7
[2]
Reveal mark scheme Mark scheme for question 7.4
7.5

A vaccine against E. coli is being trialled.

Suggest what this vaccine contains to cause immunity to E. coli.

[1]
Reveal mark scheme Mark scheme for question 7.5

Paper 1: Life and environmental sciences November 2020 Higher tier, Question 1 8 marks

Escherichia coli (E. coli) is a species of bacteria that can cause food poisoning.

1.1

Which term describes E. coli cells?

Tick (✓) one box.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

Some strains of E. coli are resistant to antibiotics.

Table 1 shows the number of infections caused by antibiotic resistant E. coli.

Figure for question 1

Calculate the percentage increase in the number of infections caused by antibiotic resistant E. coli between 2014 and 2018.

Use the equation:

Question 1, shown as an image
Question 1, shown as an image
[2]
Reveal mark scheme Mark scheme for question 1.2
1.3

Antibiotics are used to treat many different bacterial infections.

The government wants scientists to research and develop a new ‘antibiotic test’ that:

• takes less than 30 minutes

• shows doctors if an antibiotic is needed for an infection

• shows doctors which antibiotic to use.

Suggest two reasons why research into antibiotics is needed.

[2]
Reveal mark scheme Mark scheme for question 1.3
1.4

The new test should mean that fewer people take antibiotics.

What are two effects of fewer people taking antibiotics?

Tick (✓) two boxes.

Figure for question 1
[2]
Reveal mark scheme Mark scheme for question 1.4
1.5

A vaccine against E. coli is being trialled.

Suggest what this vaccine contains to cause immunity to E. coli.

[1]
Reveal mark scheme Mark scheme for question 1.5

Paper 1: Life and environmental sciences November 2020 Higher tier, Question 4 12 marks

Figure 3 shows part of one liver cell.

The photograph was taken with an electron microscope.

Figure for question 4
4.1

Name structure X.

[1]
Reveal mark scheme Mark scheme for question 4.1
4.2

Describe the function of mitochondria.

[3]
Reveal mark scheme Mark scheme for question 4.2
4.3

Protein synthesis occurs at ribosomes.

Describe the structure of a protein molecule.

[2]
Reveal mark scheme Mark scheme for question 4.3
4.4

The storage substance in liver cells is a carbohydrate.

Name the carbohydrate storage substance found in liver cells.

[1]
Reveal mark scheme Mark scheme for question 4.4
4.5

Electron microscopes have higher resolving power than light microscopes.

What is the resolving power of a microscope?

Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.5
4.6

An electron microscope has a magnification of × 650 000

The length of a cell structure in an image from the electron microscope was 27 mm

Calculate the real length of this cell structure in mm

Give your answer to 2 significant figures.

Question 4, shown as an image
[4]
Reveal mark scheme Mark scheme for question 4.6

Report a problem with a question on this page
What is wrong?

Goes to whoever maintains the question split. No account needed and nothing is published on this page.

Memes

Certified Combined Science: Synergy memes. Peer-reviewed by nobody.

Laugh now. Cry in the exam hall later. Then come back and do a past paper.

Link physics to ecosystems
Write ‘energy’ and pray
Me on the 6-marker that’s somehow both
Knowing biology and physics are different
Knowing they’re in the same paper
Linking photosynthesis to the energy topic
Explaining the whole universe in one 6-marker
Synergy enlightenment, ranked

Mum 💖

how's science going?? 🥰

it's synergy actually

ok sorry 💖

📱 Screen time this week · Roblox5h 33m

Synergy was not achieved

Synergy starter pack

Bunsen left on yellow flameGoggles on your foreheadRuler for every graph everThis website
Two of each, technically