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AQA GCSE Combined Science: Trilogy

Topic questions Cell biology Mitosis

Mitosis

6 questions · 72 marks · about 1.5 hours

Mitosis questions

AQA 8464 Mitosis 6 questions

Biology Paper 1 June 2025 Foundation tier, Question 1 11 marks

This question is about cells.

Figure 1 shows a muscle cell.

Figure for question 1
1.1

The nucleus and cytoplasm are parts of a muscle cell.

Draw one line from each part of the muscle cell to the correct label from Figure 1.

Figure for question 1
[2]
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1.2

What is the function of the nucleus?

[1]
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1.3

What part of a cell controls the movement of substances into the cell?

[1]
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1.4

Figure 2 shows a bacterial cell.

Figure for question 1

What type of cell is the bacterial cell in Figure 2 ?

Tick () one box.

Figure for question 1
[1]
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1.5

Which are two features of bacterial cells?

Tick () two boxes.

Figure for question 1
[2]
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1.6

Stem cells are cells that are not specialised.

Stem cells can be collected from human bone marrow.

What type of stem cells are found in bone marrow?

Tick () one box.

Figure for question 1
[1]
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1.7

Which process produces stem cells in humans?

Tick () one box.

Figure for question 1
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1.8

Stem cells can be used to produce blood cells.

A blood transfusion is when a patient is given blood cells.

Table 1 compares two different methods of providing blood cells that can be given to a patient.

Figure for question 1

A scientist stated:

β€˜Blood cells produced from stem cells are better to use for a blood transfusion than blood cells from a donation.’

Suggest two reasons that support the scientist’s statement.

[2]
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Biology Paper 1 June 2024 Higher tier, Question 6 11 marks

Smoking increases the risk of lung cancer.

6.1

Figure 5 shows a lung cell dividing.

Figure for question 6

Describe the process of the cell cycle shown in Figure 5.

[4]
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6.2

Lung cancer is malignant.

Explain what is meant by a malignant tumour.

[3]
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6.3

Smoking can damage the lungs in different ways.

Figure 6 shows alveoli from the lungs of two people.

Figure for question 6

Person A and person B do the same exercise.

Explain why person B breathes much faster than person A during the exercise.

[4]
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Biology Paper 1 June 2022 Foundation tier, Question 6 14 marks

This question is about cell division.

6.1
Figure for question 6
[1]
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6.2

Figure 9 shows how a fertilised egg cell can produce specialised cells.

Figure for question 6

Name Process A.

[1]
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6.3

How many cell divisions are needed to form a 16-cell embryo from the original fertilised egg cell?

Question 6, shown as an image
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6.4

In humans a fertilised egg cell contains 23 pairs of chromosomes.

How many chromosomes will there be in each of the embryo cells?

[1]
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6.5

Figure 10 represents a cell cycle for a human embryonic cell.

Figure for question 6

Describe one change in the cell that occurs during each of the stages of the cell cycle.

[3]
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6.6

Cell division is important in the growth of multicellular organisms.

Figure 11 shows the mean height of boys and of girls from birth to age 18 years.

Figure for question 6

Compare the growth of boys with the growth of girls.

Use data from Figure 11 in your answer.

[6]
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6.7

Give one way that cell division by mitosis is important in fully grown animals.

[1]
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Biology Paper 1 June 2022 Higher tier, Question 2 14 marks

This question is about cell division.

2.1

Write the biological structures from the box in the correct order of size.

Figure for question 2
[1]
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2.2
Figure for question 2

Figure 3 shows how a fertilised egg cell can produce specialised cells.

Figure for question 2

Name Process A.

[1]
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2.3

How many cell divisions are needed to form a 16-cell embryo from the original fertilised egg cell?

Question 2, shown as an image
[1]
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2.4

In humans a fertilised egg cell contains 23 pairs of chromosomes. How many chromosomes will there be in each of the embryo cells?

[1]
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2.5

Figure 4 represents a cell cycle for a human embryonic cell.

Figure for question 2

Describe one change in the cell that occurs during each of the stages of the cell cycle.

[3]
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2.6

Cell division is important in the growth of multicellular organisms.

Figure 5 shows the mean height of boys and of girls from birth to age 18 years.

Figure for question 2

Compare the growth of boys with the growth of girls. Use data from Figure 5 in your answer.

[6]
Reveal mark scheme Mark scheme for question 2.6
2.7

Give one way that cell division by mitosis is important in fully grown animals.

[1]
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Biology Paper 1 June 2018 Foundation tier, Question 5 8 marks

Cells divide in a series of stages called the cell cycle.

Stage 2 of the cycle is mitosis.

Figure 10 shows a simplified cell cycle for a human body cell.

Figure for question 5
5.1

Draw one line from each stage in the cell cycle to what happens during that stage.

What happens during that Stage in the cell cycle stage

Figure for question 5
[2]
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5.2

The mass of DNA in a human body cell at the start of the cell cycle is 6 picograms.

What mass of DNA will be in each of the new cells produced by this cell division?

Tick one box.

Figure for question 5
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5.3

Stem cells are undifferentiated cells.

Which statement about stem cells is correct?

Tick one box.

Figure for question 5
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5.4

Stem cells from human embryos can differentiate into most types of human cell.

Research is being done into the use of embryonic stem cells in medical treatments.

The long-term effects of using embryonic stem cells in patients are not well understood.

In therapeutic cloning, human embryos are produced using a donated human egg cell and a cell from the patient.

β€’ The embryo produced contains the same genetic information as the patient.

β€’ Stem cells are taken from the embryo and stimulated to divide to form cells the patient needs.

β€’ The embryo is then destroyed.

Suggest two advantages of therapeutic cloning.

[2]
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5.5

Suggest two disadvantages of therapeutic cloning.

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Biology Paper 1 June 2018 Higher tier, Question 6 14 marks

This question is about stem cells.

6.1

Give one place in a plant where stem cells are found.

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6.2

What is one economic use of plant stem cells? Tick one box.

Figure for question 6
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6.3

Embryonic stem cells divide by mitosis. Figure 9 represents a cell cycle for a human embryonic stem cell.

Figure for question 6

The mass of DNA in the cell at the start of the cycle is 6 picograms.

Question 6, shown as an image

Convert 6 picograms to grams. Give your answer in standard form.

[1]
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6.4

The time taken for this complete cell cycle is 15 hours. Calculate how many hours the cell spent in mitosis. Give your answer to 3 significant figures.

Question 6, shown as an image
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6.5

Describe what happens in each of the three stages of the cell cycle.

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6.6

Figure 10 shows how embryonic stem cells are produced in therapeutic cloning for use in patients.

Figure for question 6

Give two advantages and two disadvantages of therapeutic cloning in medical treatments. Use Figure 10 to help you.

Disadvantage 2

[4]
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