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AQA GCSE Combined Science: Synergy

Topic questions Human physiology Blood glucose regulation

Blood glucose regulation

7 questions · 75 marks · about 1.5 hours

Blood glucose regulation questions

AQA 8465 Blood glucose regulation 7 questions

Paper 1: Life and environmental sciences June 2025 Foundation tier, Question 8 11 marks

Control of blood glucose concentration is an example of homeostasis.

8.1

Give one other condition that is controlled by homeostasis in humans.

Do not refer to blood glucose concentration in your answer.

[1]
Reveal mark scheme Mark scheme for question 8.1
8.2

Figure 8 shows the blood glucose concentration of a person after eating a meal.

Figure for question 8

Calculate the increase in blood glucose concentration between 0 minutes and 50 minutes after the meal.

Use Figure 8.

_ Increase = ______________________ arbitrary units

[2]
Reveal mark scheme Mark scheme for question 8.2
8.3

Table 3 shows the blood glucose concentration between 70 minutes and 120 minutes after the meal.

Figure for question 8

Complete Figure 8.

You should:

maths symbol plot the data from Table 3

maths symbol draw a line of best fit between 60 minutes and 120 minutes.

[3]
Reveal mark scheme Mark scheme for question 8.3
8.4

After a meal, the blood glucose concentration increases and then decreases.

Describe how the pancreas causes blood glucose concentration to decrease.

[2]
Reveal mark scheme Mark scheme for question 8.4
8.5

Which substance do animal cells use to store glucose?

Tick (✓) one box.

Cellulose

Glycogen

Lactic acid

Starch

[1]
Reveal mark scheme Mark scheme for question 8.5
8.6

People with Type 2 diabetes often have high blood glucose concentration.

Give two lifestyle changes to treat Type 2 diabetes.

Question 8, shown as an image

maths symbol

[2]
Reveal mark scheme Mark scheme for question 8.6

Paper 1: Life and environmental sciences June 2025 Higher tier, Question 1 11 marks

Control of blood glucose concentration is an example of homeostasis.

1.1

Give one other condition that is controlled by homeostasis in humans.

Do not refer to blood glucose concentration in your answer.

[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

Figure 1 shows the blood glucose concentration of a person after eating a meal.

Figure for question 1

Calculate the increase in blood glucose concentration between 0 minutes and 50 minutes after the meal.

Use Figure 1.

_ Increase = ______________________ arbitrary units

[2]
Reveal mark scheme Mark scheme for question 1.2
1.3

Table 1 shows the blood glucose concentration between 70 minutes and 120 minutes after the meal.

Figure for question 1

Complete Figure 1.

You should:

maths symbol plot the data from Table 1

maths symbol draw a line of best fit between 60 minutes and 120 minutes.

[3]
Reveal mark scheme Mark scheme for question 1.3
1.4

After a meal, the blood glucose concentration increases and then decreases.

Describe how the pancreas causes blood glucose concentration to decrease.

[2]
Reveal mark scheme Mark scheme for question 1.4
1.5

Which substance do animal cells use to store glucose?

Tick (✓) one box.

Cellulose

Glycogen

Lactic acid

Starch

[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

People with Type 2 diabetes often have high blood glucose concentration.

Give two lifestyle changes to treat Type 2 diabetes.

Question 1, shown as an image

maths symbol

[2]
Reveal mark scheme Mark scheme for question 1.6

Paper 2: Life and environmental sciences June 2022 Foundation tier, Question 1 9 marks

Hormones are released by glands.

1.1

Which organ system produces hormones?

Tick (✓) one box.

Circulatory system

Digestive system

Endocrine system

[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

How are hormones transported around the body?

Tick (✓) one box.

Through the bloodstream

Through the muscles

Through the nerves

[1]
Reveal mark scheme Mark scheme for question 1.2
1.3

Figure 1 shows some of the organs in the human body.

Figure for question 1

Which organ is the pituitary gland?

Tick (✓) one box.

A B C D

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

Which organ produces oestrogen?

Tick (✓) one box.

A B C D

[1]
Reveal mark scheme Mark scheme for question 1.4
1.5

Homeostasis is the control of the body’s internal conditions.

Which internal body condition is controlled by homeostasis?

Tick (✓) one box.

Body temperature

Muscle contraction

Nerve impulses

[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

Homeostasis also controls blood glucose concentration.

Figure 2 shows the change in blood glucose concentration in a person during 180 minutes.

Figure for question 1

When did the person start eating a meal?

Use Figure 2.

Tick (✓) one box.

P Q R

[1]
Reveal mark scheme Mark scheme for question 1.6
1.7

When blood glucose concentration is high the hormone insulin is released into the blood.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.7
1.8

When will the concentration of insulin in the blood be the greatest?

Use Figure 2.

Tick (✓) one box.

P Q R

[1]
Reveal mark scheme Mark scheme for question 1.8
1.9

What might have caused the fall in blood glucose concentration at 150 minutes?

[1]
Reveal mark scheme Mark scheme for question 1.9

Paper 1: Life and environmental sciences November 2021 Foundation tier, Question 8 11 marks

The endocrine system releases hormones into the blood.

Figure 10 shows some endocrine glands and some target organs.

Figure for question 8
8.1

Which structure is the pituitary gland?

Tick (✓) one box.

W X Y Z

[1]
Reveal mark scheme Mark scheme for question 8.1
8.2

Which is the main target organ of the hormone insulin?

Tick (✓) one box.

Kidney Liver Pancreas

[1]
Reveal mark scheme Mark scheme for question 8.2
8.3

The endocrine system sends hormones to target organs.

The nervous system sends impulses to target organs.

How does the speed of movement of hormones compare with the speed of transmission of impulses?

Tick (✓) one box.

Hormones travel more slowly than impulses.

Hormones travel at the same speed as impulses.

Hormones travel more quickly than impulses.

[1]
Reveal mark scheme Mark scheme for question 8.3
8.4

The pituitary gland releases hormones, which results in widespread effects on the body.

Explain why the pituitary gland is sometimes called the ‘master gland’.

[2]
Reveal mark scheme Mark scheme for question 8.4
8.5

Figure 11 shows human blood viewed through a light microscope.

Figure for question 8

Name cell A and cell B.

[2]
Reveal mark scheme Mark scheme for question 8.5
8.6

The image of a cell has a diameter of 3.5 millimetres.

The magnification of the image is ×500.

Calculate the diameter of the real cell.

Give your answer in micrometres.

Use the equation:

Question 8, shown as an image

1 millimetre = 1000 micrometres

Diameter of the real cell = __________________ micrometres

[4]
Reveal mark scheme Mark scheme for question 8.6

Paper 1: Life and environmental sciences November 2021 Higher tier, Question 1 11 marks

The endocrine system releases hormones into the blood.

Figure 1 shows some endocrine glands and some target organs.

Figure for question 1
1.1

Which structure is the pituitary gland?

Tick (✓) one box.

W X Y Z

[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

Which is the main target organ of the hormone insulin?

Tick (✓) one box.

Kidney Liver Pancreas

[1]
Reveal mark scheme Mark scheme for question 1.2
1.3

The endocrine system sends hormones to target organs.

The nervous system sends impulses to target organs.

How does the speed of movement of hormones compare with the speed of transmission of impulses?

Tick (✓) one box.

Hormones travel more slowly than impulses.

Hormones travel at the same speed as impulses.

Hormones travel more quickly than impulses.

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

The pituitary gland releases hormones, which results in widespread effects on the body.

Explain why the pituitary gland is sometimes called the ‘master gland’.

[2]
Reveal mark scheme Mark scheme for question 1.4
1.5

Figure 2 shows human blood viewed through a light microscope.

Figure for question 1

Name cell A and cell B.

[2]
Reveal mark scheme Mark scheme for question 1.5
1.6

The image of a cell has a diameter of 3.5 millimetres.

The magnification of the image is ×500.

Calculate the diameter of the real cell.

Give your answer in micrometres.

Use the equation:

Question 1, shown as an image

1 millimetre = 1000 micrometres

Diameter of the real cell = __________________ micrometres

[4]
Reveal mark scheme Mark scheme for question 1.6

Paper 1: Life and environmental sciences November 2020 Higher tier, Question 4 12 marks

Figure 3 shows part of one liver cell.

The photograph was taken with an electron microscope.

Figure for question 4
4.1

Name structure X.

[1]
Reveal mark scheme Mark scheme for question 4.1
4.2

Describe the function of mitochondria.

[3]
Reveal mark scheme Mark scheme for question 4.2
4.3

Protein synthesis occurs at ribosomes.

Describe the structure of a protein molecule.

[2]
Reveal mark scheme Mark scheme for question 4.3
4.4

The storage substance in liver cells is a carbohydrate.

Name the carbohydrate storage substance found in liver cells.

[1]
Reveal mark scheme Mark scheme for question 4.4
4.5

Electron microscopes have higher resolving power than light microscopes.

What is the resolving power of a microscope?

Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.5
4.6

An electron microscope has a magnification of × 650 000

The length of a cell structure in an image from the electron microscope was 27 mm

Calculate the real length of this cell structure in mm

Give your answer to 2 significant figures.

Question 4, shown as an image
[4]
Reveal mark scheme Mark scheme for question 4.6

Paper 2: Life and environmental sciences November 2020 Foundation tier, Question 3 10 marks

Diabetes is a condition where the concentration of sugar in the blood can become too high.

3.1

Which chemical decreases the concentration of sugar in the blood?

Tick (✓) one box.

Figure for question 3
[1]
Reveal mark scheme Mark scheme for question 3.1
3.2

Which organ monitors and controls the concentration of sugar in the blood?

Tick (✓) one box.

Figure for question 3
[1]
Reveal mark scheme Mark scheme for question 3.2
3.3

A company produces two breakfast cereals.

In a 30 g serving:

maths symbol cereal A contains 11 g of sugar

maths symbol cereal B contains 25% less sugar than cereal A.

Calculate 25% of 11 g

Question 3, shown as an image
[2]
Reveal mark scheme Mark scheme for question 3.3
3.4

Calculate the mass of sugar in a 30 g serving of cereal B.

Use your answer from Question 03.3.

Question 3, shown as an image
[1]
Reveal mark scheme Mark scheme for question 3.4
3.5

Decreasing sugar in the diet can help prevent Type 2 diabetes.

Give one other health benefit of eating less sugar.

[1]
Reveal mark scheme Mark scheme for question 3.5
3.6

Taking regular exercise can improve health.

Table 2 shows how walking quickly or running may reduce the risk of developing different medical conditions.

The greater the percentage reduction in risk, the less chance there is of developing the medical condition.

Figure for question 3

Compare the effects of walking quickly with the effects of running on the medical conditions given in Table 2.

[4]
Reveal mark scheme Mark scheme for question 3.6

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