Biology Paper 2 June 2025 Foundation tier, Question 16 12 marks
A student wants to find how effective three antibiotics are for treating a range of bacterial infections.
This is their method:
• Spread bacteria across an agar plate.
• Soak discs with different antibiotics (A, B and C) and place them on the surface of the agar plate.
• Leave the plate to incubate for 5 days.
The student’s results are shown in the diagram.
Antibiotic discs
Which antibiotics are the most and least effective at inhibiting bacteria growth?
Most effective antibiotic A B C
Least effective antibiotic A B C
Explain your answers. Use the diagram.
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Suggest two improvements to the method to increase validity of the investigation.
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Bacteria are one cause of communicable disease.
Outline the role of the immune system of the human body in defence against disease.
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Tuberculosis (TB) is caused by bacteria. The bacteria usually attack the lungs.
It is estimated that 8.7 million people develop TB worldwide each year.
1.1 million of these people are estimated to have HIV.
Calculate the percentage of people who develop TB worldwide each year who are estimated to have HIV.
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Infection with HIV makes you more likely to develop TB.
State one reason why having HIV makes you more likely to develop TB.
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Antibiotics are developed to kill bacteria.
Bacteria have appeared that antibiotics can not kill.
Explain how bacteria could have evolved to become antibiotic resistant.
Use ideas about natural selection.
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