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OCR GCSE Combined Science

Topic questions Health and disease Cardiovascular disease

Cardiovascular disease

6 questions · 24 marks · about 30 minutes

Cardiovascular disease questions

TopicCardiovascular disease

OCR J250 Cardiovascular disease 6 questions

Biology Paper 2 June 2025 Foundation tier, Question 4 1 mark

Cardiovascular diseases are treated in different ways.

The table shows some treatments for cardiovascular disease.

TreatmentDescription
AHeart bypassA new blood vessel is inserted when the coronary artery is blocked.
BHeart transplantA new heart from a donor is inserted.
CStatinsA pill is ingested which reduces cholesterol in the blood.
DStentA small tube is inserted to open up a blocked blood vessel.

Which treatment does not involve surgery?

Question 4, shown as an image
[1]
Reveal mark scheme Mark scheme for question 4

Biology Paper 2 June 2024 Foundation tier, Question 13 5 marks

New medicines are developed all the time.

(a)

Insulin is a protein used to treat diabetes. The human stomach contains an enzyme that is specific to proteins like insulin.

Suggest why it is difficult to develop an insulin medicine that is swallowed.

[2]
Reveal mark scheme Mark scheme for question 13(a)
(b)

Which type of medicine has been developed to treat HIV?

Question 13, shown as an image

antibiotic antigen antiseptic antiviral

[1]
Reveal mark scheme Mark scheme for question 13(b)
(c)

Some diseases are treated by changes to lifestyle.

Complete these sentences about cardiovascular disease.

The risk of cardiovascular disease is reduced by a........ low in saturated fat.

This reduces the risk of blocked arteries therefore allowing more oxygen to be transported to the

........ muscle in the ventricle wall.

[2]
Reveal mark scheme Mark scheme for question 13(c)

Biology Paper 8 June 2023 Higher tier, Question 9 1 mark

A stent is a small wire structure. It is placed inside the artery that supplies the heart muscle with

Figure for question 9

Why would someone need a stent fitting?

A A high-fat diet has resulted in fatty deposits inside their arteries.

B Drinking too much alcohol has caused cirrhosis.

C Lack of exercise has reduced the strength of their heart muscles.

D Smoking has damaged the blood vessels in their lungs.

Question 9, shown as an image
[1]
Reveal mark scheme Mark scheme for question 9

Biology Paper 8 November 2021 Higher tier, Question 9 1 mark

One method of surgical treatment for cardiovascular disease involves inserting a metal or plastic tube into the coronary artery.

How will this surgical treatment help to improve the condition of a patient who has cardiovascular disease?

A It increases blood flow to the lungs.

B It increases oxygen supply to the heart muscle.

C It prevents blood flow through the damaged artery.

D It prevents oxygenated and deoxygenated blood mixing.

Question 9, shown as an image
[1]
Reveal mark scheme Mark scheme for question 9

Biology Paper 8 June 2019 Higher tier, Question 9 1 mark

The graph shows the survival rates for two groups of patients diagnosed with ≥ 50% blockage of a coronary artery. One group was treated with surgery, the other group were treated with medication.

Figure for question 9

How many years after diagnosis was there the biggest difference in survival rates between the two types of treatment?

Years after diagnosis
A2 – 4
B6 – 8
C10 – 12
D13 – 15
Question 9, shown as an image
[1]
Reveal mark scheme Mark scheme for question 9

Biology Paper 8 June 2018 Higher tier, Question 12 15 marks

(a)

Cardiovascular disease (CVD) is a major cause of death in the UK.

Look at the diagram of the external features of a heart.

Figure for question 12
(a)(i)

The coronary artery supplies the cardiac muscle with oxygen.

Label the diagram to show the position of one of the coronary arteries.

[1]
Reveal mark scheme Mark scheme for question 12(a)(i)
(a)(ii)

Angina is a symptom of CVD. Pain from angina is caused by cardiac muscle respiring anaerobically.

Explain why angina causes pain.

[2]
Reveal mark scheme Mark scheme for question 12(a)(ii)
(b)(i)

A 55 year old patient has severe chest pains due to a narrowed coronary artery.

The diagram shows the cross-section of a normal coronary artery and the patient’s artery.

Figure for question 12

Normal coronary artery
Patient’s coronary artery

The cross-sectional area of the normal coronary artery lumen is 18.1 mm2.

Calculate the cross-sectional area of the lumen of the patient’s artery.

Use the equations:

Question 12, shown as an image

Give your answer to 2 significant figures.

[3]
Reveal mark scheme Mark scheme for question 12(b)(i)
(b)(ii)

Calculate the percentage reduction in cross-sectional area for the lumen of the patient’s artery.

[1]
Reveal mark scheme Mark scheme for question 12(b)(ii)
(b)(iii)

CVD can be treated by different combinations of lifestyle changes, medicine and surgery.

Look at the information on CVD and how much the coronary artery has been narrowed

Figure for question 12

Justify why the patient would need surgery.

[2]
Reveal mark scheme Mark scheme for question 12(b)(iii)
(c)

* Doctors rely on different types of surgery to treat cardiovascular disease.

The table shows features of three surgical treatments.

Figure for question 12

Evaluate the three surgical treatments and decide which would be the best type of surgery for the 55 year old patient.

[6]
Reveal mark scheme Mark scheme for question 12(c)

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