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AQA GCSE Combined Science: Trilogy

Topic questions Health and disease Communicable disease

Communicable disease

18 questions · 211 marks · about 4 hours

Communicable disease questions

AQA 8464 Communicable disease 18 questions

Biology Paper 1 June 2025 Foundation tier, Question 2 13 marks

Photosynthesis is important for plant growth.

A student used pondweed to investigate photosynthesis.

Figure 3 shows the apparatus used.

Figure for question 2

This is the method used.

1. Set up the apparatus as shown in Figure 3.

2. Switch on the lamp.

3. After 1 hour, record the volume of oxygen collected in the measuring cylinder.

4. Repeat steps 1 to 3 a further four times, placing the lamp at different distances from the pondweed.

2.1

What are two control variables the student should use in the investigation?

Tick () two boxes.

Figure for question 2
[2]
Reveal mark scheme Mark scheme for question 2.1
2.2

Table 2 shows the results.

Figure for question 2

Describe the trend shown in Table 2.

[1]
Reveal mark scheme Mark scheme for question 2.2
2.3

Figure 4 shows the volume of oxygen when the lamp was 10 cm from the pondweed.

Figure for question 2

What volume of oxygen is shown in Figure 4 ?

Question 2, shown as an image
[1]
Reveal mark scheme Mark scheme for question 2.3
2.4

The student repeated the investigation using a measuring cylinder with smaller

Question 2, shown as an image

What did using smaller intervals improve?

Tick () one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.4
2.5

The student did the investigation at 10 °C.

The student repeated the investigation at 20 °C.

Complete the sentence.

Choose the answer from the box.

Figure for question 2

Compared to the results at 10 °C, the volumes of oxygen collected

in one hour at 20 °C would be.

Give a reason for your answer.

[2]
Reveal mark scheme Mark scheme for question 2.5
2.6

Photosynthesis is important for apple trees.

Figure 5 shows a section through the leaf of an apple tree.

Figure for question 2

What is tissue A ?

Tick () one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.6
2.7

The cells in tissue A contain chloroplasts.

What is the name of the green chemical in chloroplasts?

[1]
Reveal mark scheme Mark scheme for question 2.7
2.8

Apple scab is a disease of apple trees.

Apple scab is caused by a fungus.

Figure 6 shows a leaf from an apple tree infected with apple scab fungus.

Figure for question 2

How could the fungal infection be removed from the tree?

Tick () one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.8
2.9

Infection with apple scab fungus decreases the number of chloroplasts in the leaves.

Explain why apple trees with apple scab fungus produce smaller apples than apple trees that are not infected.

[3]
Reveal mark scheme Mark scheme for question 2.9

Biology Paper 1 June 2025 Foundation tier, Question 6, also on the Higher paper 12 marks

Chickenpox is an infectious disease that affects young children.

6.1

One symptom of chickenpox is small blisters on the skin.

Suggest one way chickenpox spreads from an infected person to other people.

[1]
Reveal mark scheme Mark scheme for question 6.1
6.2

Chickenpox is caused by a type of pathogen that cannot be treated with antibiotics.

Give the reason why chickenpox cannot be treated with antibiotics.

[1]
Reveal mark scheme Mark scheme for question 6.2
6.3

A vaccine that could be used to protect against chickenpox has been produced.

What does a vaccine contain that causes a person to become immune to a disease?

[1]
Reveal mark scheme Mark scheme for question 6.3
6.4

Give three reasons why a new vaccine must be tested.

[3]
Reveal mark scheme Mark scheme for question 6.4
6.5

Explain how a vaccine for chickenpox gives immunity against the disease.

You should refer to how the body responds to:

• the vaccine

• chickenpox pathogens that enter the body after vaccination.

[6]
Reveal mark scheme Mark scheme for question 6.5

Biology Paper 1 June 2025 Higher tier, Question 2, also on the Foundation paper 12 marks

Chickenpox is an infectious disease that affects young children.

2.1

One symptom of chickenpox is small blisters on the skin.

Suggest one way chickenpox spreads from an infected person to other people.

[1]
Reveal mark scheme Mark scheme for question 2.1
2.2

Chickenpox is caused by a type of pathogen that cannot be treated with antibiotics.

Give the reason why chickenpox cannot be treated with antibiotics.

[1]
Reveal mark scheme Mark scheme for question 2.2
2.3

A vaccine that could be used to protect against chickenpox has been produced.

What does a vaccine contain that causes a person to become immune to a disease?

[1]
Reveal mark scheme Mark scheme for question 2.3
2.4

Give three reasons why a new vaccine must be tested.

[3]
Reveal mark scheme Mark scheme for question 2.4
2.5

Explain how a vaccine for chickenpox gives immunity against the disease.

You should refer to how the body responds to:

• the vaccine

• chickenpox pathogens that enter the body after vaccination.

[6]
Reveal mark scheme Mark scheme for question 2.5

Biology Paper 1 June 2024 Foundation tier, Question 4 10 marks

This question is about disease.

Gonorrhoea is a sexually transmitted disease.

4.1

Which is a symptom of gonorrhoea?

Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.1
4.2

Table 2 shows the number of reported cases of gonorrhoea for 5 cities.

Figure for question 4

The number of cases of gonorrhoea in each city might not be accurate.

Suggest one reason why.

[1]
Reveal mark scheme Mark scheme for question 4.2
4.3

Which is the best way to present the data from Table 2 ?

Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.3
4.4

The data is given as per 100 000 of the population and not as the total number of people with gonorrhoea.

Suggest why.

[1]
Reveal mark scheme Mark scheme for question 4.4
4.5

Deposits can form in coronary arteries.

The deposits are called plaques.

Plaques cause damage to the arteries.

Figure 6 shows plaques in a coronary artery.

Figure for question 4

Which two factors increase the risk of plaques forming in the coronary artery?

Tick (✓) two boxes.

Figure for question 4
[2]
Reveal mark scheme Mark scheme for question 4.5
4.6

Which treatment can be used for the plaques in Figure 6 ?

Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.6
4.7

A heart attack can happen when plaques block a coronary artery.

During a heart attack muscle cells in the heart die.

Explain how the blockage can lead to the death of muscle cells in the heart.

[3]
Reveal mark scheme Mark scheme for question 4.7

Biology Paper 1 June 2024 Higher tier, Question 3 12 marks

This question is about communicable diseases.

Measles is a communicable disease caused by a pathogen.

3.1

What type of microorganism causes measles?

[1]
Reveal mark scheme Mark scheme for question 3.1
3.2

Vaccinations help reduce the spread of measles.

Suggest two ways the spread of measles can be reduced.

Do not refer to vaccination in your answer.

[2]
Reveal mark scheme Mark scheme for question 3.2
3.3

Describe how the measles vaccine helps a person to become immune to the measles pathogen.

[4]
Reveal mark scheme Mark scheme for question 3.3
3.4

Norovirus is a type of virus.

Explain how viruses cause illness.

[2]
Reveal mark scheme Mark scheme for question 3.4
3.5

Drugs can help to reduce the symptoms of the norovirus infection.

New drugs must go through clinical trials before being licensed for use.

Give three reasons why clinical trials are needed.

[3]
Reveal mark scheme Mark scheme for question 3.5

Biology Paper 1 June 2023 Foundation tier, Question 6 14 marks

Communicable and non-communicable diseases are major causes of ill health.

6.1

Which disease is a non-communicable disease?

Tick (✓) one box.

Figure for question 6
[1]
Reveal mark scheme Mark scheme for question 6.1
6.2

Obesity is a risk factor for many non-communicable diseases.

Give one non-communicable disease that obesity is a risk factor for.

Do not refer to the diseases given in Question 06.1 in your answer.

[1]
Reveal mark scheme Mark scheme for question 6.2
6.3

National policies are used to help people who are obese to lose weight.

One national policy is to reduce the amount of sugar added to food and drinks.

Suggest one other national policy that could help people to lose weight.

[1]
Reveal mark scheme Mark scheme for question 6.3
6.4

Body mass index (BMI) is one measure of obesity.

BMI is calculated using the equation:

Question 6, shown as an image

Table 4 shows how BMI is used to describe an adult’s BMI category.

Figure for question 6

A person is 1.64 m tall and has a mass of 69 kg.

Determine the BMI category for this person.

Use the BMI equation and Table 4.

The person’s BMI category is

[3]
Reveal mark scheme Mark scheme for question 6.4
6.5

Scientists investigated the effect of smoking and of BMI on the birth mass of babies.

Women’s BMI categories were determined before the women became pregnant.

Suggest why BMI categories were determined before the women became pregnant.

[1]
Reveal mark scheme Mark scheme for question 6.5
6.6

Figure 9 shows the results.

Figure for question 6

Give two conclusions that can be made from Figure 9.

[2]
Reveal mark scheme Mark scheme for question 6.6
6.7

Measles is a communicable disease.

A virus causes measles.

Describe how the measles virus is transferred from person to person.

[2]
Reveal mark scheme Mark scheme for question 6.7
6.8

Athlete’s foot is a communicable disease.

A fungus causes athlete’s foot.

The athlete’s foot fungus infects the skin on feet.

Scientists estimate that 17% of the UK population have athlete’s foot.

The estimated UK population is 67 961 900

Calculate how many people are estimated to have athlete’s foot.

[2]
Reveal mark scheme Mark scheme for question 6.8
6.9

Athlete’s foot fungus grows in moist conditions.

Suggest one way a person could reduce their chance of catching athlete’s foot.

[1]
Reveal mark scheme Mark scheme for question 6.9

Biology Paper 1 June 2023 Higher tier, Question 1 14 marks

Communicable and non-communicable diseases are major causes of ill health.

1.1

Which disease is a non-communicable disease?

Tick (✓) one box.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

Obesity is a risk factor for many non-communicable diseases.

Give one non-communicable disease that obesity is a risk factor for.

Do not refer to the diseases given in Question 01.1 in your answer.

[1]
Reveal mark scheme Mark scheme for question 1.2
1.3

National policies are used to help people who are obese to lose weight.

One national policy is to reduce the amount of sugar added to food and drinks.

Suggest one other national policy that could help people to lose weight.

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

Body mass index (BMI) is one measure of obesity.

BMI is calculated using the equation:

Question 1, shown as an image

Table 1 shows how BMI is used to describe an adult’s BMI category.

Figure for question 1

A person is 1.64 m tall and has a mass of 69 kg.

Determine the BMI category for this person.

Use the BMI equation and Table 1.

The person’s BMI category is

[3]
Reveal mark scheme Mark scheme for question 1.4
1.5

Scientists investigated the effect of smoking and of BMI on the birth mass of babies.

Women’s BMI categories were determined before the women became pregnant.

Suggest why BMI categories were determined before the women became pregnant.

[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

Figure 1 shows the results.

Figure for question 1

Give two conclusions that can be made from Figure 1.

[2]
Reveal mark scheme Mark scheme for question 1.6
1.7

Measles is a communicable disease.

A virus causes measles.

Describe how the measles virus is transferred from person to person.

[2]
Reveal mark scheme Mark scheme for question 1.7
1.8

Athlete’s foot is a communicable disease.

A fungus causes athlete’s foot.

The athlete’s foot fungus infects the skin on feet.

Scientists estimate that 17% of the UK population have athlete’s foot.

The estimated UK population is 67 961 900

Calculate how many people are estimated to have athlete’s foot.

[2]
Reveal mark scheme Mark scheme for question 1.8
1.9

Athlete’s foot fungus grows in moist conditions.

Suggest one way a person could reduce their chance of catching athlete’s foot.

[1]
Reveal mark scheme Mark scheme for question 1.9

Biology Paper 1 June 2022 Foundation tier, Question 3 9 marks

This question is about disease.

Rose black spot is a disease where black spots develop on the leaves of rose plants.

3.1

What type of pathogen causes rose black spot disease?

Tick (✓) one box.

Figure for question 3
[1]
Reveal mark scheme Mark scheme for question 3.1
3.2

Plants with rose black spot disease often have yellow leaves.

Suggest one reason why the leaves are yellow instead of green.

[1]
Reveal mark scheme Mark scheme for question 3.2
3.3

Explain why plants with yellow leaves grow slowly.

[2]
Reveal mark scheme Mark scheme for question 3.3
3.4

The spread of rose black spot can be controlled using different methods.

Draw one line from each method of control to the explanation of how it works.

Method of control
Explanation

Figure for question 3
[2]
Reveal mark scheme Mark scheme for question 3.4
3.5

Tobacco plants may become infected with a pathogen called TMV.

What type of pathogen is TMV?

Tick (✓) one box.

Figure for question 3
[1]
Reveal mark scheme Mark scheme for question 3.5
3.6

Malaria is a disease caused by a protist.

How is the malaria pathogen transferred to humans?

[1]
Reveal mark scheme Mark scheme for question 3.6
3.7

How can the spread of malaria pathogens be reduced?

Tick (✓) one box.

Figure for question 3
Question 3, shown as an image
[1]
Reveal mark scheme Mark scheme for question 3.7

Biology Paper 1 June 2022 Foundation tier, Question 5 9 marks

Bacteria can cause a variety of diseases in humans.

5.1

What are two similarities between a bacterial cell and an animal cell?

Tick (✓) two boxes.

Figure for question 5
[2]
Reveal mark scheme Mark scheme for question 5.1
5.2

Salmonella food poisoning is caused by bacteria in food.

Give one symptom of salmonella food poisoning.

Do not refer to vomiting or diarrhoea in your answer.

[1]
Reveal mark scheme Mark scheme for question 5.2
5.3

What is the name of the first antibiotic developed?

[1]
Reveal mark scheme Mark scheme for question 5.3
5.4

A child with a severe bacterial infection was given a course of antibiotics.

Figure 7 shows how the concentration of live bacteria in the child’s body changed when taking the course of antibiotics.

Figure for question 5

The concentration of live bacteria in the body continued to increase after starting the course of antibiotics.

Suggest one reason why.

[1]
Reveal mark scheme Mark scheme for question 5.4
5.5

After 3 days of taking the antibiotic:

• the child felt better

• there were still bacteria in the child’s body.

Why did the child feel better?

Tick (✓) one box.

Figure for question 5
[1]
Reveal mark scheme Mark scheme for question 5.5
5.6

Suggest why doctors do not give antibiotics to patients with minor infections.

[1]
Reveal mark scheme Mark scheme for question 5.6
5.7

Figure 8 shows blood viewed using a microscope.

Figure for question 5

A vaccine will stimulate the production of antibodies.

Which part of the blood in Figure 8 produces antibodies?

Tick (✓) one box.

Figure for question 5
[1]
Reveal mark scheme Mark scheme for question 5.7
5.8

Which part of the blood in Figure 8 starts the clotting process?

Tick (✓) one box.

Figure for question 5
[1]
Reveal mark scheme Mark scheme for question 5.8

Biology Paper 1 June 2022 Higher tier, Question 1 9 marks

Bacteria can cause a variety of diseases in humans.

1.1

What are two similarities between a bacterial cell and an animal cell? Tick (✓) two boxes.

Figure for question 1
[2]
Reveal mark scheme Mark scheme for question 1.1
1.2

Salmonella food poisoning is caused by bacteria in food. Give one symptom of salmonella food poisoning. Do not refer to vomiting or diarrhoea in your answer.

[1]
Reveal mark scheme Mark scheme for question 1.2
1.3

What is the name of the first antibiotic developed?

[1]
Reveal mark scheme Mark scheme for question 1.3
1.4

A child with a severe bacterial infection was given a course of antibiotics.

Figure 1 shows how the concentration of live bacteria in the child’s body changed when taking the course of antibiotics.

Figure for question 1

The concentration of live bacteria in the body continued to increase after starting the course of antibiotics. Suggest one reason why.

[1]
Reveal mark scheme Mark scheme for question 1.4
1.5

After 3 days of taking the antibiotic:

• the child felt better

• there were still bacteria in the child’s body.

Why did the child feel better? Tick (✓) one box.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

Suggest why doctors do not give antibiotics to patients with minor infections.

[1]
Reveal mark scheme Mark scheme for question 1.6
1.7

Figure 2 shows blood viewed using a microscope.

Figure for question 1

A vaccine will stimulate the production of antibodies. Which part of the blood in Figure 2 produces antibodies? Tick (✓) one box.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.7
1.8

Which part of the blood in Figure 2 starts the clotting process? Tick (✓) one box.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.8

Biology Paper 1 November 2021 Foundation tier, Question 2 10 marks

Antibiotics are used to treat bacterial infections.

2.1

Which substance is used as an antibiotic?

Tick (✓) one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.1
2.2

Gonorrhoea and chlamydia are two sexually transmitted infections.

Gonorrhoea and chlamydia infections can be treated with antibiotics.

Give one symptom of gonorrhoea.

[1]
Reveal mark scheme Mark scheme for question 2.2
2.3

A scientist investigated which antibiotics were most effective at treating gonorrhoea

and chlamydia.

This is the method used.

1. Grow gonorrhoea bacteria in a Petri dish.

2. Prepare four different antibiotic solutions, A, B, C and D, of the same concentration.

3. Cut four filter paper discs to the same size.

4. Soak each paper disc in a different antibiotic solution.

5. Put the four paper discs into the Petri dish.

6. Repeat steps 3 to 5 using a Petri dish with chlamydia bacteria growing in it.

7. Keep both Petri dishes at 25 °C for 3 days.

Give two control variables used in this investigation.

[2]
Reveal mark scheme Mark scheme for question 2.3
2.4

Figure 2 shows the results.

A clear area around a paper disc is where the antibiotic has killed the bacteria.

Figure for question 2

Which antibiotic did not kill either type of bacterium?

Tick (✓) one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.4
2.5

Which antibiotic would be the most effective to treat a person with a gonorrhoea infection?

Tick (✓) one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.5
2.6

Which antibiotic would be the most effective to treat a person who had both gonorrhoea and chlamydia infections?

Tick (✓) one box.

Figure for question 2
[1]
Reveal mark scheme Mark scheme for question 2.6
2.7

Antibiotics cannot be used to treat HIV infections.

Suggest one reason why.

[1]
Reveal mark scheme Mark scheme for question 2.7
2.8

Fungi can cause an infection of the fingernails and toenails.

Fungal nail infections can spread from one person to another person.

Some people go to nail salons to have their nails shaped and painted.

Suggest one way workers in nail salons can reduce the risk of infections being spread.

[1]
Reveal mark scheme Mark scheme for question 2.8
2.9

Suggest one reason why fungal infection of toenails is more common than fungal infection of fingernails.

[1]
Reveal mark scheme Mark scheme for question 2.9

Biology Paper 1 November 2021 Higher tier, Question 4 12 marks

Pathogens are microorganisms that cause diseases. Gonorrhoea, malaria and measles are three diseases in humans.

4.1

Draw one line from each disease to the pathogen that causes the disease.

Figure for question 4
[3]
Reveal mark scheme Mark scheme for question 4.1
4.2

Malaria is transmitted by mosquitos. Male mosquitos can be sterilised so they are infertile. The spread of malaria is reduced by releasing sterile mosquitos into the environment. Explain how releasing sterile mosquitos reduces the spread of malaria.

[2]
Reveal mark scheme Mark scheme for question 4.2
4.3

Pathogens also cause diseases in plants. Figure 4 shows a rose black spot fungal spore and a tobacco mosaic virus.

Figure for question 4

Name the piece of equipment used to view the virus.

[1]
Reveal mark scheme Mark scheme for question 4.3
4.4

How many times longer is the fungal spore than the virus? Use Figure 4.

Question 4, shown as an image
[3]
Reveal mark scheme Mark scheme for question 4.4
4.5

Explain why plants infected with tobacco mosaic virus grow slowly.

[3]
Reveal mark scheme Mark scheme for question 4.5

Biology Paper 1 November 2020 Foundation tier, Question 4 14 marks

Pathogens cause infectious diseases.

4.1

Draw one line from each disease to the type of pathogen that causes the disease.

Figure for question 4
[2]
Reveal mark scheme Mark scheme for question 4.1
4.2

The body defends itself against pathogens in different ways.

Give two ways that the body prevents pathogens entering the body.

[2]
Reveal mark scheme Mark scheme for question 4.2
4.3

If pathogens do enter the body the immune system tries to destroy the pathogens. Describe how the immune system defends the body against disease.

[6]
Reveal mark scheme Mark scheme for question 4.3
4.4

Give one reason why antibiotics cannot be used to treat HIV infections.

[1]
Reveal mark scheme Mark scheme for question 4.4
4.5

Give two ways to prevent the spread of HIV.

[2]
Reveal mark scheme Mark scheme for question 4.5
4.6

Some people with a HIV infection develop AIDS. Some people with AIDS may die from a different type of infection, such as a chest infection.

Why do people with AIDS die from a different type of infection? Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.6

Biology Paper 1 November 2020 Higher tier, Question 4 12 marks

Cells are the basic units of all forms of life.

4.1

Describe four differences between a bacterial cell and a plant cell.

[4]
Reveal mark scheme Mark scheme for question 4.1
4.2

Gonorrhoea is a bacterial disease. A new vaccine is being developed against gonorrhoea. Describe how a vaccine would work to prevent gonorrhoea.

[4]
Reveal mark scheme Mark scheme for question 4.2
4.3

Another disease caused by bacteria is salmonella food poisoning. In the UK, chickens are vaccinated against Salmonella bacteria to reduce the number of cases of food poisoning in humans.

Explain how vaccinating chickens reduces the number of cases of salmonella food poisoning.

[2]
Reveal mark scheme Mark scheme for question 4.3
4.4

Give one way that the spread of salmonella food poisoning from one human to another is controlled. Do not refer to vaccination in your answer.

[1]
Reveal mark scheme Mark scheme for question 4.4
4.5

The number of cases of salmonella food poisoning is usually higher in summer than in winter. Suggest one reason why.

[1]
Reveal mark scheme Mark scheme for question 4.5

Biology Paper 1 June 2019 Foundation tier, Question 5 8 marks

Malaria is a disease transmitted by mosquitos.

Figure 9 shows information about the number of deaths from malaria.

Figure for question 5
5.1

Calculate the decrease in the number of deaths between 2000 and 2015.

Question 5, shown as an image
[2]
Reveal mark scheme Mark scheme for question 5.1
5.2

Which time period shows the greatest decrease in the number of deaths?

Tick (✓) one box.

Figure for question 5
[1]
Reveal mark scheme Mark scheme for question 5.2
5.3

A student looked at Figure 9 and concluded that there were 800 000 deaths from malaria in 2002.

Suggest one reason why this conclusion might not be correct.

[1]
Reveal mark scheme Mark scheme for question 5.3
5.4

What type of pathogen causes malaria?

Tick (✓) one box.

Figure for question 5
[1]
Reveal mark scheme Mark scheme for question 5.4
5.5

Scientists are developing a vaccine against malaria.

Suggest how a vaccine against malaria could reduce the spread of the disease.

[2]
Reveal mark scheme Mark scheme for question 5.5
5.6

Give one way of controlling the spread of malaria.

Do not refer to a vaccine in your answer.

[1]
Reveal mark scheme Mark scheme for question 5.6

Biology Paper 1 June 2019 Higher tier, Question 4 17 marks

Pathogens are microorganisms that cause infectious diseases.

4.1

What type of pathogen causes malaria? Tick (✓) one box.

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4.1
4.2

Give two methods used to prevent people catching malaria. Give a reason why each method works.

[4]
Reveal mark scheme Mark scheme for question 4.2
4.3

Describe two differences between a bacterial cell and a eukaryotic cell.

[2]
Reveal mark scheme Mark scheme for question 4.3
4.4

A scientist investigated the population growth of bacteria in a culture solution. At the start of the investigation the culture solution contained all the nutrients the bacteria needed. The scientist determined the number of living bacterial cells in the solution every hour over two days. Figure 5 shows the apparatus used.

Figure for question 4

Describe why there are air holes in the cap of the culture bottle.

[1]
Reveal mark scheme Mark scheme for question 4.4
4.5

Figure 6 shows the scientist’s results.

Figure for question 4

Give one reason for what is happening to the number of bacteria at each of the stages.

[4]
Reveal mark scheme Mark scheme for question 4.5
4.6

Figure 7 shows two cubes. Cube X represents a bacterial cell. Cube Y represents a small multicellular organism.

Figure for question 4

A bacterial cell can absorb all the nutrients it needs by diffusion through its outer surface. Explain why a multicellular organism cannot absorb all the nutrients it needs by diffusion through its outer surface. You must include calculations in your answer. Use Figure 7.

[5]
Reveal mark scheme Mark scheme for question 4.6

Biology Paper 1 June 2018 Foundation tier, Question 1 13 marks

Figure 1 shows one type of white blood cell.

Figure for question 1
1.1

What is structure A ?

Tick one box.

Figure for question 1
[1]
Reveal mark scheme Mark scheme for question 1.1
1.2

White blood cells help to defend the body against pathogens.

How do the white blood cells do this?

Tick three boxes.

Figure for question 1
[3]
Reveal mark scheme Mark scheme for question 1.2
1.3

Measles is a serious disease. A person can die from measles.

Figure 2 shows the number of cases of measles in England and Wales between 2012 and 2015

Figure for question 1

Use Figure 2 to calculate the decrease in the number of cases of measles between 2012 and 2015

[2]
Reveal mark scheme Mark scheme for question 1.3
1.4

Suggest one reason for the decrease in the number of cases of measles between 2012 and 2015

[1]
Reveal mark scheme Mark scheme for question 1.4
1.5

Antibiotics cannot be used to treat measles.

Suggest why.

[1]
Reveal mark scheme Mark scheme for question 1.5
1.6

Gonorrhoea is a disease caused by a bacterium.

Gonorrhoea can be treated with antibiotics.

Give one other way to control the spread of gonorrhoea.

[1]
Reveal mark scheme Mark scheme for question 1.6
1.7

A scientist investigated how effective different antibiotics were at killing gonorrhoea bacteria.

This is the method used.

1. Grow gonorrhoea bacteria on agar in a Petri dish.

2. Place one paper disc soaked in water onto the agar.

3. Place four other paper discs, each soaked in a different antibiotic, A, B, C, and D onto the agar.

4. Use the same sized paper discs and the same concentration of each antibiotic.

5. Incubate the Petri dish for 3 days.

Figure 3 shows the scientist’s results.

A clear area around the disc means the antibiotic has killed the bacteria.

Figure for question 1

Give one control variable the scientist used.

[1]
Reveal mark scheme Mark scheme for question 1.7
1.8

Suggest why one disc was soaked in water.

[1]
Reveal mark scheme Mark scheme for question 1.8
1.9

Which antibiotic in Figure 3 would be the best to treat gonorrhoea?

Give a reason for your answer.

[2]
Reveal mark scheme Mark scheme for question 1.9

Biology Paper 1 June 2018 Higher tier, Question 5 11 marks

Measles is a serious disease. A person can die from measles. Table 3 shows the number of medically confirmed cases of measles in England and Wales between 2012 and 2015

Figure for question 5
5.1

Suggest one reason why the actual number of cases of measles in England and Wales might be higher than is shown in Table 3

[1]
Reveal mark scheme Mark scheme for question 5.1
5.2

Calculate the percentage decrease in the number of medically confirmed cases of measles between 2012 and 2015

Question 5, shown as an image
[2]
Reveal mark scheme Mark scheme for question 5.2
5.3

One reason for the decrease in the number of cases of measles is that more children were vaccinated against the disease. Vaccinating a large proportion of the population reduces the spread of the measles virus. Explain why.

[2]
Reveal mark scheme Mark scheme for question 5.3
5.4

Figure 8 shows the concentration of measles antibodies in the blood of a boy.

Figure for question 5

Explain the differences between antibody production after the vaccine injection and after exposure to the measles virus. You should include data from Figure 8

[6]
Reveal mark scheme Mark scheme for question 5.4

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