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Edexcel GCSE Combined Science

Topic questions Cell biology Diffusion

Diffusion

9 questions · 85 marks · about 1.5 hours

Diffusion questions

Edexcel 1SC0 Diffusion 9 questions

Paper 1: Biology 1 June 2025 Foundation tier, Question 6 13 marks

(a)

Figure 12 shows a beaker containing a potato cylinder in distilled water.

Figure for question 6

Explain why the mass of this potato cylinder will change when it is placed in distilled water.

[3]
Reveal mark scheme Mark scheme for question 6(a)
(b)

A scientist investigated the rate of diffusion using three agar cubes of different sizes.

Each cube contained a pH indicator that changed from pink to colourless when placed in acid.

The cubes were placed in a beaker containing an acid.

Figure 13 shows some information about each cube.

Figure for question 6
(b)(i)

Calculate the volume of cube C.

........ cm3

[2]
Reveal mark scheme Mark scheme for question 6(b)(i)
(b)(ii)

Explain the difference in the times taken for cubes A and B to become colourless.

[2]
Reveal mark scheme Mark scheme for question 6(b)(ii)
(c)

* (c) Liquid agar was poured into a Petri dish and allowed to set.

A well was cut in the centre of the set agar.

Kiwi fruit juice was poured into the well.

Kiwi fruit juice contains an enzyme that causes set agar to break down into a liquid.

Figure 14 shows the results after 30 minutes.

Figure for question 6

Devise a plan to investigate the effect of different concentrations of kiwi fruit juice on the breakdown of set agar, using the equipment shown in Figure 14.

Your plan should include:

โ€ข measurements that need to be taken

โ€ข variables that need to be controlled.

[6]
Reveal mark scheme Mark scheme for question 6(c)

Paper 1: Biology 1 June 2025 Higher tier, Question 2 7 marks

(a)

Figure 2 shows a beaker containing a potato cylinder in distilled water.

Figure for question 2

Explain why the mass of this potato cylinder will change when it is placed in distilled water.

[3]
Reveal mark scheme Mark scheme for question 2(a)
(b)

A scientist investigated the rate of diffusion using three agar cubes of different sizes.

Each cube contained a pH indicator that changed from pink to colourless when placed in acid.

The cubes were placed in a beaker containing an acid.

Figure 3 shows some information about each cube.

Figure for question 2
(b)(i)

Calculate the volume of cube C.

[2]
Reveal mark scheme Mark scheme for question 2(b)(i)
(b)(ii)

Explain the difference in the times taken for cubes A and B to become colourless.

[2]
Reveal mark scheme Mark scheme for question 2(b)(ii)

Paper 2: Biology 2 June 2025 Higher tier, Question 3 9 marks

(a)

A teacher was demonstrating a process to students.

The teacher had a beaker of water and added five drops of food colouring to the beaker.

Figure for question 3
(a)(i)

State the process being demonstrated.

[1]
Reveal mark scheme Mark scheme for question 3(a)(i)
(a)(ii)

A student asked if different food colourings spread evenly in the same amount of time.

Give two variables that would need to be controlled if the investigation was repeated with different food colourings.

[2]
Reveal mark scheme Mark scheme for question 3(a)(ii)
(b)

The teacher repeated this process with water at different temperatures. Figure 7 shows the results of this experiment.

Figure for question 3
(b)(i)

Draw a line graph to show the results in Figure 7.

[4]
Reveal mark scheme Mark scheme for question 3(b)(i)
(b)(ii)

Explain why the time taken decreased.

[2]
Reveal mark scheme Mark scheme for question 3(b)(ii)

Paper 2: Biology 2 June 2024 Foundation tier, Question 4 11 marks

In humans, gas exchange occurs in the alveoli of the lungs.

Figure 6 shows the structure of an alveolus and its blood supply.

Figure for question 4
(a)

Which process moves carbon dioxide from the blood into the alveolus?

Question 4, shown as an image
[1]
Reveal mark scheme Mark scheme for question 4(a)
(b)

State one adaptation of an alveolus that increases the rate of gas exchange.

[1]
Reveal mark scheme Mark scheme for question 4(b)
(c)

Describe how blood is moved from the heart to the lungs.

[2]
Reveal mark scheme Mark scheme for question 4(c)
(d)

Figure 7 shows the heart rate of a person before, during and after exercise.

Figure for question 4
(d)(i)

Describe the trend shown in Figure 7.

Use data from Figure 7 to support your answer.

[2]
Reveal mark scheme Mark scheme for question 4(d)(i)
(d)(ii)

Explain the trend shown in Figure 7 from 5 minutes to 25 minutes.

[2]
Reveal mark scheme Mark scheme for question 4(d)(ii)
(d)(iii)

The stroke volume is the volume of blood pumped during one beat of the heart.

At 25 minutes the stroke volume was 0.13 dm3.

Calculate the cardiac output of the heart of this person at 25 minutes.

Use the equation

cardiac output = stroke volumemaths symbolheart rate

........ dm3 per minute

[3]
Reveal mark scheme Mark scheme for question 4(d)(iii)

Paper 1: Biology 1 June 2022 Foundation tier, Question 3 10 marks

Alcohol is broken down by liver cells.

(a)

Which process moves alcohol from the blood into the liver cells?

Question 3, shown as an image
[1]
Reveal mark scheme Mark scheme for question 3(a)
(b)

If a person drinks too much alcohol, liver cells die and the person can develop cirrhosis of the liver.

The relative risk of developing cirrhosis of the liver is affected by two factors.

1. The volume of alcohol a person drinks in one week.

2. Whether the person drinks the alcohol on its own or with a meal.

Figure 5 shows how these two factors affect the relative risk of people developing cirrhosis of the liver.

Figure for question 3

Number of units of alcohol consumed per week

Figure 5

(b)(i)

Person A drinks alcohol on its own.

Person B drinks alcohol with their meals.

Calculate the difference in risk for these two people when each one drinks 28 units of alcohol per week.

[3]
Reveal mark scheme Mark scheme for question 3(b)(i)
(b)(ii)

Using evidence from Figure 5, state two pieces of health advice for people about drinking alcohol.

[2]
Reveal mark scheme Mark scheme for question 3(b)(ii)
(c)

Cystic fibrosis is a genetic condition that can also cause liver disease.

(c)(i)

State where genes are found in cells.

[1]
Reveal mark scheme Mark scheme for question 3(c)(i)
(c)(ii)

Figure 6 shows the inheritance of cystic fibrosis in a family.

F represents the dominant allele that does not cause cystic fibrosis.

f represents the recessive allele that causes cystic fibrosis.

person A (Ff) person B

Figure for question 3

person C person D person E (ff)

Figure 6

A scientist states that the genotype of person B is Ff.

Explain why the scientist is correct.

[2]
Reveal mark scheme Mark scheme for question 3(c)(ii)
(c)(iii)

State the genotype of person C.

[1]
Reveal mark scheme Mark scheme for question 3(c)(iii)

Paper 2: Biology 2 November 2021 Foundation tier, Question 4 10 marks

(a)

Figure 7 shows a single-celled pond organism (Amoeba proteus).

Figure for question 4
(a)(i)

Which row of the table allows the net diffusion of oxygen into Amoeba proteus ?

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4(a)(i)
(a)(ii)

Amoeba proteus uses oxygen for aerobic respiration.

Complete the equation for aerobic respiration.

glucose + oxygen maths symbol........ +........ (+ energy is released)

[1]
Reveal mark scheme Mark scheme for question 4(a)(ii)
(b)

Humans breathe faster when they exercise.

(b)(i)

Which two changes allow the rate of respiration in the muscle to increase?

Figure for question 4
[1]
Reveal mark scheme Mark scheme for question 4(b)(i)
(b)(ii)

Figure 8 shows breathing data for a human at rest and when running at 5 metres per second on a running machine.

Figure for question 4

Calculate the mean volume of air breathed per minute when running at 5 metres per second.

Give your answer to one decimal place.

........ dm3 per minute

[2]
Reveal mark scheme Mark scheme for question 4(b)(ii)
(b)(iii)

Devise an investigation to compare the mean number of breaths per minute for men, with the mean number of breaths per minute for women, when running at 5 metres per second on a running machine.

[4]
Reveal mark scheme Mark scheme for question 4(b)(iii)
(c)

Whilst running, the leg muscles of an athlete tightened up, causing cramp.

Name the product of anaerobic respiration that can cause cramp.

[1]
Reveal mark scheme Mark scheme for question 4(c)

Paper 2: Biology 2 November 2021 Higher tier, Question 3 9 marks

Figure 6 shows the structure and actual size of red blood cells (erythrocytes).

Figure for question 3

red blood cells side view of red blood cell (cut)

(Source: ยฉ N.Vinoth Narasingam/Shutterstock)

Figure 6

(a)(i)

Calculate the image size of the top view of this red blood cell if this cell is

Question 3, shown as an image

Give your answer in mm.

........ mm

[2]
Reveal mark scheme Mark scheme for question 3(a)(i)
(a)(ii)

Explain how the shape of a red blood cell is related to its function.

[3]
Reveal mark scheme Mark scheme for question 3(a)(ii)
(a)(iii)

State the role of haemoglobin inside the red blood cell.

[1]
Reveal mark scheme Mark scheme for question 3(a)(iii)
(b)

Some blood transfusions contain red blood cells.

Red blood cells are stored in a solution containing 5.0% glucose and 0.9% salt.

Explain why red blood cells cannot be stored in pure water.

[3]
Reveal mark scheme Mark scheme for question 3(b)

Paper 1: Biology 1 November 2020 Foundation tier, Question 1 6 marks

(a)

Figure 1 shows three cells.

Figure for question 1
(a)(i)

What is structure X ?

Question 1, shown as an image
[1]
Reveal mark scheme Mark scheme for question 1(a)(i)
(a)(ii)

The bacterial cell in Figure 1 has a flagellum.

State the function of a flagellum.

[1]
Reveal mark scheme Mark scheme for question 1(a)(ii)
(a)(iii)

Give one other difference between the bacterial cell and the animal cell shown in Figure 1.

[1]
Reveal mark scheme Mark scheme for question 1(a)(iii)
(b)

Substances move into and out of cells.

How does oxygen move into and out of cells?

Question 1, shown as an image
[1]
Reveal mark scheme Mark scheme for question 1(b)
(c)

A plant leaf cell is 0.04 mm long.

Calculate the length of the image after this cell has been magnified 500 times.

length of image =........ mm

[2]
Reveal mark scheme Mark scheme for question 1(c)

Paper 1: Biology 1 November 2020 Foundation tier, Question 2 10 marks

(a)

A student placed three different sized cubes of agar jelly into separate beakers containing the same concentration of hydrochloric acid.

The cubes contained a pink indicator.

This indicator becomes clear when in contact with an acid.

Figure 2 shows the results of the investigation after the cubes had been in the acid for 120 seconds.

Figure for question 2
(a)(i)

The distance from the outside of cube B to the pink area was 3 mm.

Calculate the distance diffused by hydrochloric acid in one second.

........ mm

[2]
Reveal mark scheme Mark scheme for question 2(a)(i)
(a)(ii)

The student wanted to confirm their results.

Give one improvement the student should make to this investigation to confirm their results.

[1]
Reveal mark scheme Mark scheme for question 2(a)(ii)
(b)

Devise a method, using cubes of agar jelly, to investigate how temperature affects the rate of diffusion.

[3]
Reveal mark scheme Mark scheme for question 2(b)
(c)

Some substances move into and out of cells by active transport.

Which is the correct description of the movement of a substance by active transport?

Question 2, shown as an image
[1]
Reveal mark scheme Mark scheme for question 2(c)
(d)

Some drugs used to treat cancer are taken into cells by active transport.

Figure 3 shows some causes of preventable cases of cancer in 2015.

Figure for question 2
(d)(i)

What is the percentage of preventable cases of cancer that are caused by tobacco?

Question 2, shown as an image
[1]
Reveal mark scheme Mark scheme for question 2(d)(i)
(d)(ii)

In 2015, data from Cancer Research UK suggested that 163 440 cases of cancer could have been prevented.

Calculate the number of preventable cases of cancer caused by alcohol.

Give your answer to the nearest whole number.

number of preventable cases of cancer caused by alcohol........

[2]
Reveal mark scheme Mark scheme for question 2(d)(ii)

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