BREAKING
Student sits three sciences, gets two grades, wants a recount★Cover teacher explains biology using only physics equations★Nation in shock as student wears goggles on actual eyes★
  1. Home
  2. GCSE
  3. Combined Science
  4. Edexcel
  5. Spread of disease

Edexcel GCSE Combined Science

Topic questions Health and disease Spread of disease

Spread of disease

12 questions · 114 marks · about 2 hours

Spread of disease questions

Edexcel 1SC0 Spread of disease 12 questions

Paper 1: Biology 1 June 2025 Foundation tier, Question 5 11 marks

(a)

Figure 10 shows the number of new cases of chlamydia diagnosed in England from 2013 to 2022.

Figure for question 5
(a)(i)

Which type of organism causes chlamydia?

Question 5, shown as an image
[1]
Reveal mark scheme Mark scheme for question 5(a)(i)
(a)(ii)

Calculate the increase in the number of new cases of chlamydia diagnosed from 2020 to 2022.

........ cases

[1]
Reveal mark scheme Mark scheme for question 5(a)(ii)
(a)(iii)

Tuberculosis is a disease that is spread through airborne droplets.

Give two ways of reducing or preventing the spread of tuberculosis.

[2]
Reveal mark scheme Mark scheme for question 5(a)(iii)
(b)

Obesity is a risk factor for some non‑communicable diseases.

(b)(i)

State why liver disease is a non-communicable disease.

[1]
Reveal mark scheme Mark scheme for question 5(b)(i)
(b)(ii)

The waist‑to‑hip ratio can be used to show if excess weight is a health risk.

An adult has a waist measurement of 80 cm and a hip measurement of 90 cm.

Calculate the waist‑to‑hip ratio for this adult, using the equation:

Question 5, shown as an image

Give your answer to two decimal places.

waist‑to‑hip ratio........

[2]
Reveal mark scheme Mark scheme for question 5(b)(ii)
(b)(iii)

Figure 11 shows the health risk of some waist‑to‑hip ratios.

Figure for question 5

Explain the health risk for a female with a waist‑to‑hip ratio of 0.75.

[2]
Reveal mark scheme Mark scheme for question 5(b)(iii)
(c)

Cancer occurs when cell division by mitosis is uncontrolled.

Describe the properties of cells produced by mitosis.

[2]
Reveal mark scheme Mark scheme for question 5(c)

Paper 1: Biology 1 June 2025 Higher tier, Question 1 9 marks

(a)

Tuberculosis is a disease that is spread through airborne droplets.

Give two ways of reducing or preventing the spread of tuberculosis.

[2]
Reveal mark scheme Mark scheme for question 1(a)
(b)

Obesity is a risk factor for some non‑communicable diseases.

(b)(i)

State why liver disease is a non-communicable disease.

[1]
Reveal mark scheme Mark scheme for question 1(b)(i)
(b)(ii)

The waist‑to‑hip ratio can be used to show if excess weight is a health risk.

An adult has a waist measurement of 80 cm and a hip measurement of 90 cm.

Calculate the waist‑to‑hip ratio for this adult, using the equation:

Question 1, shown as an image

Give your answer to two decimal places.

waist‑to‑hip ratio........

[2]
Reveal mark scheme Mark scheme for question 1(b)(ii)
(b)(iii)

Figure 1 shows the health risk of some waist‑to‑hip ratios.

Figure for question 1

Explain the health risk for a female with a waist‑to‑hip ratio of 0.75.

[2]
Reveal mark scheme Mark scheme for question 1(b)(iii)
(c)

Cancer occurs when cell division by mitosis is uncontrolled.

Describe the properties of cells produced by mitosis.

[2]
Reveal mark scheme Mark scheme for question 1(c)

Paper 1: Biology 1 June 2025 Higher tier, Question 4 9 marks

(a)

The pathogen Vibrio cholerae causes the disease cholera.

Figure 5 shows Vibrio cholerae bacteria.

Figure for question 4
(a)(i)

Complete the table to show the function of structure P and structure Q.

Figure for question 4
[2]
Reveal mark scheme Mark scheme for question 4(a)(i)
(a)(ii)

On the original image, the length of one bacterial cell is 12 mm.

The actual length of this bacterial cell is 2.0 µ m.

Calculate the magnification.

[2]
Reveal mark scheme Mark scheme for question 4(a)(ii)
(a)(iii)

State one symptom of the disease caused by Vibrio cholerae.

[1]
Reveal mark scheme Mark scheme for question 4(a)(iii)
(a)(iv)

State how the disease caused by Vibrio cholerae is transmitted.

[1]
Reveal mark scheme Mark scheme for question 4(a)(iv)
(b)

Describe the specific immune response when a pathogen infects the body.

[3]
Reveal mark scheme Mark scheme for question 4(b)

Paper 1: Biology 1 June 2024 Foundation tier, Question 6 13 marks

(a)

Malaria is a disease that causes damage to the blood and liver.

(a)(i)

Which type of pathogen causes malaria?

Question 6, shown as an image
[1]
Reveal mark scheme Mark scheme for question 6(a)(i)
(a)(ii)

State how the pathogen that causes malaria is spread.

[1]
Reveal mark scheme Mark scheme for question 6(a)(ii)
(b)

Measles is a disease caused by a virus.

Figure 9 shows the number of measles cases reported in England and Wales from 1985 to 2015.

Figure for question 6

Explain one conclusion that can be made about the change in the number of measles cases reported from 1985 to 2015.

[2]
Reveal mark scheme Mark scheme for question 6(b)
(c)

Describe two ways the immune system will respond to an infection by a pathogen.

[2]
Reveal mark scheme Mark scheme for question 6(c)
(d)
(d)(i)

Beriberi is a disease caused by a lack of vitamin B1 in the diet.

Give one reason why beriberi is classed as a non‑communicable disease.

[1]
Reveal mark scheme Mark scheme for question 6(d)(i)
(d)(ii)

*(ii) Beriberi can affect reflexes.

Figure 10 shows a reflex arc.

Figure for question 6

When the skin is pricked by a pin, electrical impulses travel through a reflex arc.

Describe the path taken by electrical impulses from the skin to the muscles in the arm.

Include the names of neurones X, Y and Z in your answer.

[6]
Reveal mark scheme Mark scheme for question 6(d)(ii)

Paper 1: Biology 1 June 2024 Higher tier, Question 2 7 marks

(a)

Malaria is a disease that causes damage to the blood and liver.

(a)(i)

Which type of pathogen causes malaria?

Question 2, shown as an image
[1]
Reveal mark scheme Mark scheme for question 2(a)(i)
(a)(ii)

State how the pathogen that causes malaria is spread.

[1]
Reveal mark scheme Mark scheme for question 2(a)(ii)
(b)

Measles is a disease caused by a virus.

Figure 2 shows the number of measles cases reported in England and Wales from 1985 to 2015.

Figure for question 2

Explain one conclusion that can be made about the change in the number of measles cases reported from 1985 to 2015.

[2]
Reveal mark scheme Mark scheme for question 2(b)
(c)

Describe two ways the immune system will respond to an infection by a pathogen.

[2]
Reveal mark scheme Mark scheme for question 2(c)
(d)

Beriberi is a disease caused by a lack of vitamin B1 in the diet.

Give one reason why beriberi is classed as a non‑communicable disease.

[1]
Reveal mark scheme Mark scheme for question 2(d)

Paper 1: Biology 1 June 2022 Foundation tier, Question 1 7 marks

Some bacteria cause disease.

(a)

Which word describes an organism that causes disease?

Question 1, shown as an image
[1]
Reveal mark scheme Mark scheme for question 1(a)
(b)

Draw one straight line from each disease to the main way that the disease is spread.

disease main way the

Figure for question 1
[2]
Reveal mark scheme Mark scheme for question 1(b)
(c)

A scientist investigated the effect of temperature on the growth of bacteria.

The bacteria were grown at 10 °C and 20 °C.

The number of bacteria grown at each temperature were counted every two hours.

Figure 1 shows the result.

Figure for question 1

Figure 2 shows a graph of the results at 20 °C.

Figure for question 1
(c)(i)

Plot the points on the graph for the number of bacteria at 10 °C.

The first two points have been plotted for you.

[1]
Reveal mark scheme Mark scheme for question 1(c)(i)
(c)(ii)

Draw a line of best fit on the graph for 10 °C.

[1]
Reveal mark scheme Mark scheme for question 1(c)(ii)
(c)(iii)

Describe how the growth of bacteria at 10 °C was different from the growth of bacteria at 20 °C.

[2]
Reveal mark scheme Mark scheme for question 1(c)(iii)

Paper 1: Biology 1 June 2022 Higher tier, Question 2 9 marks

(a)

Figure 2 shows the number of people diagnosed with sexually transmitted infections (STIs) in the UK during 2017.

Figure for question 2
(a)(i)

State the sexually transmitted infection that has the median number of people diagnosed.

[1]
Reveal mark scheme Mark scheme for question 2(a)(i)
(a)(ii)

The population of the UK in 2017 was 66 million people.

Calculate the total number of people diagnosed with chlamydia in the UK in 2017.

........ people

[2]
Reveal mark scheme Mark scheme for question 2(a)(ii)
(a)(iii)

State why chlamydia can be described as a communicable disease.

[1]
Reveal mark scheme Mark scheme for question 2(a)(iii)
(a)(iv)

Give one way the transmission of chlamydia can be prevented.

[1]
Reveal mark scheme Mark scheme for question 2(a)(iv)
(a)(v)

Explain why chlamydia can be treated with antibiotics.

[2]
Reveal mark scheme Mark scheme for question 2(a)(v)
(b)

HIV is another sexually transmitted infection.

Explain how HIV can lead to the onset of AIDS.

[2]
Reveal mark scheme Mark scheme for question 2(b)

Paper 1: Biology 1 November 2021 Foundation tier, Question 6 13 marks

(a)

Name the organisation which defines health as a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.

[1]
Reveal mark scheme Mark scheme for question 6(a)
(b)

Tuberculosis (TB) is a communicable disease.

(b)(i)

State two ways that communicable diseases are different from non-communicable diseases.

[2]
Reveal mark scheme Mark scheme for question 6(b)(i)
(b)(ii)

Explain one way that the spread of tuberculosis (TB) can be reduced or prevented.

[2]
Reveal mark scheme Mark scheme for question 6(b)(ii)
(b)(iii)
Question 6, shown as an image
Figure for question 6

Complete the table to show the student’s data.

[2]
Reveal mark scheme Mark scheme for question 6(b)(iii)
(c)

* (c) Describe how the physical barriers and chemical defences of the human body provide protection from diseases.

[6]
Reveal mark scheme Mark scheme for question 6(c)

Paper 1: Biology 1 November 2021 Higher tier, Question 2 9 marks

(a)

Name the organisation which defines health as a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.

[1]
Reveal mark scheme Mark scheme for question 2(a)
(b)

Tuberculosis (TB) is a communicable disease.

(b)(i)

State two ways that communicable diseases are different from non-communicable diseases.

[2]
Reveal mark scheme Mark scheme for question 2(b)(i)
(b)(ii)

Explain one way that the spread of tuberculosis (TB) can be reduced or prevented.

[2]
Reveal mark scheme Mark scheme for question 2(b)(ii)
(b)(iii)
Question 2, shown as an image
Figure for question 2

Complete the table to show the student’s data.

Figure for question 2
[2]
Reveal mark scheme Mark scheme for question 2(b)(iii)
(c)

Explain why people with AIDS are more susceptible to TB.

[2]
Reveal mark scheme Mark scheme for question 2(c)

Paper 1: Biology 1 November 2020 Foundation tier, Question 5 11 marks

(a)

Measles is a communicable disease caused by a virus.

(a)(i)

What can a virus also be classified as?

Question 5, shown as an image
[1]
Reveal mark scheme Mark scheme for question 5(a)(i)
(a)(ii)

Give one reason why measles is described as a communicable disease.

[1]
Reveal mark scheme Mark scheme for question 5(a)(ii)
(b)

The human immunodeficiency virus (HIV) can cause AIDS.

Which type of cell is destroyed by the HIV virus?

Question 5, shown as an image
[1]
Reveal mark scheme Mark scheme for question 5(b)
(c)

Describe how the specific immune system defends the body against disease.

[3]
Reveal mark scheme Mark scheme for question 5(c)
(d)

Figure 7 shows the number of people per million of the population in five European countries who were diagnosed with measles in one year.

Figure for question 5
(d)(i)

The population of Belgium in that year was 11.18 million.

Calculate the number of people in Belgium diagnosed with measles.

Give your answer to three significant figures.

........ people

[3]
Reveal mark scheme Mark scheme for question 5(d)(i)
(d)(ii)

Countries do not report the total number of people diagnosed with measles. Countries report the number of people diagnosed with measles per million of the population.

Give one reason why this is better.

[1]
Reveal mark scheme Mark scheme for question 5(d)(ii)
(d)(iii)

Give one reason why the number of people per million diagnosed with measles is different in these countries.

[1]
Reveal mark scheme Mark scheme for question 5(d)(iii)

Paper 1: Biology 1 November 2020 Higher tier, Question 1 9 marks

(a)

The human immunodeficiency virus (HIV) can cause AIDS.

Which type of cell is destroyed by the HIV virus?

Question 1, shown as an image
[1]
Reveal mark scheme Mark scheme for question 1(a)
(b)

Describe how the specific immune system defends the body against disease.

[3]
Reveal mark scheme Mark scheme for question 1(b)
(c)

Figure 1 shows the number of people per million of the population in five European countries who were diagnosed with measles in one year.

Figure for question 1
(c)(i)

The population of Belgium in that year was 11.18 million.

Calculate the number of people in Belgium diagnosed with measles.

Give your answer to three significant figures.

........ people

[3]
Reveal mark scheme Mark scheme for question 1(c)(i)
(c)(ii)

Countries do not report the total number of people diagnosed with measles. Countries report the number of people diagnosed with measles per million of the population.

Give one reason why this is better.

[1]
Reveal mark scheme Mark scheme for question 1(c)(ii)
(c)(iii)

Give one reason why the number of people per million diagnosed with measles is different in these countries.

[1]
Reveal mark scheme Mark scheme for question 1(c)(iii)

Paper 1: Biology 1 June 2018 Foundation tier, Question 1 7 marks

(a)

Pathogens cause disease.

Draw one straight line from each type of pathogen to the disease that is caused by that pathogen.

Figure for question 1
[2]
Reveal mark scheme Mark scheme for question 1(a)
(b)

Antibiotics can be used to treat diseases.

Antibiotics kill

Question 1, shown as an image
[1]
Reveal mark scheme Mark scheme for question 1(b)
(c)

Figure 1 shows the number of white blood cells in blood samples from three patients.

Figure for question 1

Explain why the data suggests that Patient Z has a bacterial infection.

[2]
Reveal mark scheme Mark scheme for question 1(c)
(d)

HIV is diagnosed by blood tests.

State two safety precautions that need to be taken when handling blood samples.

[2]
Reveal mark scheme Mark scheme for question 1(d)

Report a problem with a question on this page
What is wrong?

Goes to whoever maintains the question split. No account needed and nothing is published on this page.

Memes

Certified Combined Science memes. Peer-reviewed by nobody.

Laugh now. Cry in the exam hall later. Then come back and do a past paper.

Revise all three sciences
Just revise the fun one
Me the night before the chemistry paper
Knowing it's three sciences
Knowing which teacher does which
Remembering which equations are given
Remembering which science you're actually sitting today
Science enlightenment, combined

Mum 💖

which science is it today? 🥰

all of them somehow

go on genius!!! 💪

📱 Screen time this week · YouTube6h 21m

None of them were revised

Combined Science starter pack

Goggles worn on foreheadBunsen on the yellow flamePractical write-up, half doneThis website
Three sciences, four items